{"id":35871,"date":"2026-09-07T08:28:08","date_gmt":"2026-09-06T23:28:08","guid":{"rendered":"https:\/\/promea2014.com\/blog\/?p=35871"},"modified":"2026-09-07T08:28:08","modified_gmt":"2026-09-06T23:28:08","slug":"lpa%e4%bd%8e%e4%b8%8b%e8%96%ac%e3%81%ae%e5%a4%b1%e6%95%97%e3%81%af%e4%bd%95%e3%82%92%e6%84%8f%e5%91%b3%e3%81%99%e3%82%8b%e3%81%8b%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=35871","title":{"rendered":"Lp(a)\u4f4e\u4e0b\u85ac\u306e\u5931\u6557\u306f\u4f55\u3092\u610f\u5473\u3059\u308b\u304b\uff1f"},"content":{"rendered":"<p>\u5148\u9031\u306e\u9031\u672b\u3001\u5faa\u74b0\u5668\u3084\u8102\u8cea\u7570\u5e38\u306e\u5c02\u9580\u5bb6\u305f\u3061\u306fSNS\u3067\u5927\u9a12\u304e\u3067\u3057\u305f\u3002\u305d\u306e\u7406\u7531\u306f\u3001\u767b\u5834\u9593\u8fd1\u3060\u3068\u601d\u308f\u308c\u3066\u3044\u305f\u3001Lp(a)\u4f4e\u4e0b\u85ac\u306e\u30da\u30e9\u30ab\u30eb\u30bb\u30f3\u306e\u7b2cIII\u76f8\u8a66\u9a13\u3001Lp(a)HORIZON\u8a66\u9a13\u304c\u5927\u5931\u6557\u306b\u7d42\u308f\u3063\u3066\u3057\u307e\u3063\u305f\u304b\u3089\u3067\u3059\u3002\uff08<a href=\"https:\/\/www.novartis.com\/news\/media-releases\/novartis-announces-lpahorizon-phase-iii-topline-results-pelacarsen-patients-elevated-lpa-and-established-cardiovascular-disease-cvd\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09<\/p>\n<p>\u3053\u306e\u7b2cIII\u76f8\u8a66\u9a13\u306f\u3001\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea(a)\uff08Lp(a)\uff09\u304c\u4e0a\u6607\u3057\u305f\u60a3\u8005\u3067\u3001\u65e2\u5b58\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u6709\u3059\u308b\u60a3\u8005\u306b\u5bfe\u3057\u3001Lp(a)\u4f4e\u4e0b\u85ac\u306e\u30da\u30e9\u30ab\u30eb\u30bb\u30f3\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u3092\u6295\u4e0e\u3057\u307e\u3057\u305f\u3002\uff08\u8a73\u3057\u3044\u5185\u5bb9\u306f<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40185318\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09Lp(a)\u5024\u304c70 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href=\"https:\/\/medical.nikkeibp.co.jp\/leaf\/mem\/pub\/report\/202503\/587798.html\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\uff09\u306b\u3088\u308b\u3068\u3001\u3042\u308b\u5c02\u9580\u5bb6\u306f\u3001\u300c<span style=\"color: #3366ff;\">\u5b9f\u969b\u306b\u4f7f\u3048\u308b\u3088\u3046\u306b\u306a\u308b\u304b\u306f\u3001\u7b2c3\u76f8\u8a66\u9a13\u306e\u7d50\u679c\u6b21\u7b2c\u3002\u8a66\u9a13\u3067ASCVD\u30ea\u30b9\u30af\u306e\u6709\u610f\u306a\u6291\u5236\u3092\u793a\u305b\u308b\u304b\u306b\u304b\u304b\u3063\u3066\u3044\u308b<\/span>\u300d\u3068\u3057\u3064\u3064\u3082\u3001\u3000\u300c<span style=\"color: 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href=\"https:\/\/promea2014.com\/blog\/?p=30188\" target=\"_blank\" 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href=\"https:\/\/promea2014.com\/blog\/?p=6311\" target=\"_blank\" rel=\"noopener\">5\u65e5\u9593\u306e\u9ad8\u8102\u80aa\u9ad8\u30a8\u30cd\u30eb\u30ae\u30fc\u98df\u8ca0\u8377\u8a66\u9a13\uff08\u4eba\u4f53\u5b9f\u9a13\uff09\u3000\u305d\u306e2<\/a>\u300d\u53c2\u7167\uff09<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/MyLpa54645575e50b835200fa406bbd95f489-300x196-1.png\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"35869\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=35869\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/MyLpa54645575e50b835200fa406bbd95f489-300x196-1.png\" data-orig-size=\"300,196\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"MyLpa54645575e50b835200fa406bbd95f489-300&amp;#215;196\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/MyLpa54645575e50b835200fa406bbd95f489-300x196-1.png\" class=\"alignnone wp-image-35869\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2025\/10\/MyLpa54645575e50b835200fa406bbd95f489-300x196-1.png\" alt=\"\" width=\"400\" height=\"261\" \/><\/a><\/p>\n<p>\u79c1\u306eLp(a)\u306f\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u3067\u306f24.5\u3042\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u9ad8\u8102\u80aa\u98df\u3092\u98df\u3079\u59cb\u3081\u3066\u3069\u3093\u3069\u3093\u4f4e\u4e0b\u3057\u30015\u65e5\u5f8c\u306b\u306f9.2\u307e\u3067\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u307e\u305f\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=32581\" target=\"_blank\" rel=\"noopener\">Lp(a)\u306b\u5bfe\u3059\u308b\u98df\u4e8b\u3084\u904b\u52d5\u306a\u3069\u306e\u5f71\u97ff<\/a>\u300d\u306b\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u98fd\u548c\u8102\u80aa\u9178\u6442\u53d6\u3092\u5927\u304d\u304f\u6e1b\u3089\u3059\u3068\u300124\uff05\u3082Lp(a)\u304c\u5897\u52a0\u3057\u307e\u3059\u3002\u6d3b\u52d5\u6027\u306b\u3064\u3044\u3066\u3082\u6d3b\u52d5\u6027\u304c\u9ad8\u3044\u65b9\u304cLp(a)\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3057\u3001\u30de\u30e9\u30bd\u30f3\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u884c\u3046\u3068\u3001\u3069\u3093\u3069\u3093Lp(a)\u304c\u4e0a\u304c\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n<p>Lp(a)\u304c\u907a\u4f1d\u7684\u306b\u6c7a\u307e\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u306e\u3082\u30a6\u30bd\u3067\u3059\u3057\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u539f\u56e0\u3067\u3042\u308b\u3068\u3044\u3046\u306e\u3082\u30a6\u30bd\u3067\u3059\u3002<\/p>\n<p>Lp(a)\u4f4e\u4e0b\u85ac\u306e\u5931\u6557\u306f\u4f55\u3092\u610f\u5473\u3059\u308b\u304b\uff1f<\/p>\n<p>Lp(a)\u306e\u6570\u5024\u309280\uff05\u3082\u4f4e\u4e0b\u3055\u305b\u3066\u3082\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306f\u6e1b\u3089\u305b\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u8ab0\u304c\u8003\u3048\u3066\u3082\u308f\u304b\u308a\u307e\u3059\u3002\u305d\u308c\u306fLp(a)\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3092\u3002\u5c0f\u5b66\u751f\u3067\u3082\u308f\u304b\u308b\u3067\u3057\u3087\u3046\u3002\u4eca\u5f8c\u306e\u4ed6\u3082\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u306b\u3088\u3063\u3066\u306f\u3001Lp(a)\u304c\u6d88\u3048\u53bb\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u305f\u3060\u3001\u4eca\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306fLp(a)\u304c\u8d85\u60aa\u7389\u306e\u6271\u3044\u3067\u3059\u3002\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41824552\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u53c2\u7167\u3001\u4e0b\u306e\u8868\u306f\u3053\u3053\u3088\u308a\u6539\u5909\uff09<\/p>\n<table data-shading=\"custom\">\n<thead>\n<tr data-xml-align=\"left\">\n<th><span dir=\"auto\">Lp(a)\u6fc3\u5ea6 nmol\/L (mg\/dL)<\/span><\/th>\n<th><span dir=\"auto\">\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\u76f8\u5bfe\u30ea\u30b9\u30af\uff1a<\/span><br \/>\n<span dir=\"auto\">\u4e2d\u592e\u5024\uff0820 nmol\/L\u30017 mg\/dL\uff09\u3068\u6bd4\u8f03\u3057\u3066\u5897\u52a0<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span dir=\"auto\">430 nmol\/L (180 mg\/dL)<\/span><\/td>\n<td><span dir=\"auto\">4\u500d<\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\">350 nmol\/L (150 mg\/dL)<\/span><\/td>\n<td><span dir=\"auto\">3\u500d<\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\">250 nmol\/L (100 mg\/dL)<\/span><\/td>\n<td><span dir=\"auto\">2\u500d<\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\">125 nmol\/L (50 mg\/dL)<\/span><\/td>\n<td><span dir=\"auto\">1.4\u500d<\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\">75\uff5e124 nmol\/L\uff0830\uff5e49 mg\/dL\uff09<\/span><\/td>\n<td><span dir=\"auto\">1.2\u500d<\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\">&lt;75 nmol\/L (&lt;30 mg\/dL)<\/span><\/td>\n<td><span dir=\"auto\">1<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u78ba\u304b\u306b\u3001\u4e0a\u306e\u8868\u306e\u3088\u3046\u306a\u30c7\u30fc\u30bf\u3092\u51fa\u3057\u3066\u3044\u308b\u7814\u7a76\u306f\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3001\u3053\u308c\u3082\u76f8\u95a2\u95a2\u4fc2\u306a\u306e\u304b\u56e0\u679c\u95a2\u4fc2\u306a\u306e\u304b\u306f\u3001\u308f\u304b\u308a\u307e\u305b\u3093\u3002Lp(a)\u304c\u9ad8\u3044\u3088\u3046\u306a\u72b6\u614b\u3001\u98df\u4e8b\u304c\u60aa\u3044\u306e\u304b\u3001\u305d\u3082\u305d\u3082Lp(a)\u306f\u539f\u56e0\u306e\u4e00\u3064\u306a\u306e\u304b\u308f\u304b\u3089\u306a\u3044\u306e\u306b\u3001\u72af\u4eba\u6271\u3044\u3067\u3059\u3002Lp(a)\u3092\u4e0b\u3052\u3066\u3082\u30ea\u30b9\u30af\u304c\u4e0b\u304c\u3089\u306a\u3044\u306e\u3067\u3001\u72af\u4eba\u3067\u306f\u306a\u3044\u3067\u3059\u3002<\/p>\n<p>\u3055\u3089\u306b\u3001\u4e0a\u306e\u8868\u3092\u30b0\u30e9\u30d5\u306b\u3059\u308b\u3068\u4e0b\u306e\u56f3\u306e\u3088\u3046\u306a\u306e\u3067\u3059\u3002\uff08\u56f3\u306f<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36036785\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3053<\/a>\u3088\u308a\uff09<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-e1788692011415.jpg\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"35875\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=35875\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-e1788692011415.jpg\" data-orig-size=\"323,230\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"Lpaehac361f2\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-e1788692011415.jpg\" class=\"alignnone size-full wp-image-35875\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-e1788692011415.jpg\" alt=\"\" width=\"323\" height=\"230\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-e1788692011415.jpg 323w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-e1788692011415-300x214.jpg 300w\" sizes=\"auto, (max-width: 323px) 100vw, 323px\" \/><\/a><\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-1-e1788692167525.jpg\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"35876\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=35876\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-1-e1788692167525.jpg\" data-orig-size=\"540,314\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"Lpaehac361f2\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-1-e1788692167525.jpg\" class=\"alignnone size-full wp-image-35876\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-1-e1788692167525.jpg\" alt=\"\" width=\"540\" height=\"314\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-1-e1788692167525.jpg 540w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2026\/09\/Lpaehac361f2-1-e1788692167525-300x174.jpg 300w\" sizes=\"auto, (max-width: 540px) 100vw, 540px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u751f\u6daf\u306e\u7d2f\u7a4d\u306e\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u75be\u60a3\u30a4\u30d9\u30f3\u30c8\u306e\u767a\u751f\u7387\u3067\u3059\u3002Lp(a)\u304c<span dir=\"auto\">350 nmol\/L (150 mg\/dL)\uff08\u4e00\u756a\u4e0a\u306e\u8d64\u3044\u7dda\uff09\u3067\u306f\u3001\u78ba\u304b\u306b\u4ed6\u306e\u5024\u306e\u30b0\u30e9\u30d5\u3088\u308a\u3082\u767a\u751f\u7387\u306f\u9ad8\u3044\u3067\u3059\u304c\u3001\u7e26\u8ef8\u3092\u898b\u308b\u3068\u300170\u6b73\u4ed8\u8fd1\u3067\u30820.3\uff05\u7a0b\u5ea6\uff1f\u3002\u7dd1\u8272\u306e\u7dda\u304c70\u6b73\u4ed8\u8fd1\u30670.1\uff05\u7a0b\u5ea6\uff1f\u30df\u30b9\u30d7\u30ea\u3067\u3057\u3087\u3046\u306d\u3002\u6050\u3089\u304f30\uff05\u306810\uff05\u304c\u6b63\u3057\u3044\u3067\u3057\u3087\u3046\u3002\u3067\u3082\u3001\u3053\u308c\u3082Lp(a)\u3092\u4e0b\u3052\u308c\u3070\u3001\u30ea\u30b9\u30af\u304c\u4e0b\u304c\u308b\u8a3c\u62e0\u306b\u306f\u306a\u308a\u5f97\u307e\u305b\u3093\u3002<\/span><\/p>\n<p>\u3055\u3089\u306b\u3001Lp(a)\u5024\u3067\u8208\u5473\u6df1\u3044\u306e\u306f\u3001\u300c<a href=\"https:\/\/promea2014.com\/blog\/?p=6623\" target=\"_blank\" 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