{"id":3898,"date":"2018-03-21T17:52:43","date_gmt":"2018-03-21T08:52:43","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=3898"},"modified":"2018-03-21T21:57:35","modified_gmt":"2018-03-21T12:57:35","slug":"post-3898","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=3898","title":{"rendered":"HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u9ad8\u3051\u308c\u3070\u826f\u3044\u3063\u3066\u3082\u3093\u3058\u3083\u306a\u3044\uff1f\u3000\u305d\u306e3"},"content":{"rendered":"

\u4ee5\u524d\u306e\u8a18\u4e8b\u300cHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u9ad8\u3051\u308c\u3070\u826f\u3044\u3063\u3066\u3082\u3093\u3058\u3083\u306a\u3044\uff1f<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u6975\u7aef\u306b\u9ad8\u3044\u3068\u3001\u6b7b\u4ea1\u7387\u304c\u4e0a\u6607\u3059\u308b\u306e\u3067\u306f\uff1f\u3068\u3044\u3046\u7814\u7a76\u306f\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u65e5\u672c\u4eba\u306e\u3082\u306e\u3067\u306f\u306a\u3044\u306e\u3067\u3059\u304c\u3001\u5fc5\u305a\u3057\u3082HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c90mg\/L\u4ee5\u4e0a\u3067\u5fc3\u8840\u7ba1\u7cfb\u306e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u7537\u5973\u306b\u5dee\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u307e\u305a\u306f\u3001\u4eca\u56de\u306e\u7814\u7a76\u3067HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u5206\u5e03\u3092\u307f\u3066\u307f\u307e\u3057\u3087\u3046\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u53f3\u304c\u5973\u6027\u3001\u5de6\u304c\u7537\u6027\u3067\u3059\u304c\u3001\u5206\u5e03\u306e\u30d4\u30fc\u30af\u306f\u660e\u3089\u304b\u306b\u5973\u6027\u306e\u65b9\u304c\u9ad8\u3044\u3067\u3059\u3002\u3064\u307e\u308a\u3001\u5973\u6027\u306e\u65b9\u304cHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u9ad8\u3044\u4eba\u304c\u591a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

\u4e0a\u306e\u56f3\u306f\u5168\u539f\u56e0\u6b7b\u4ea1\u7387\u3092\u898b\u3066\u3044\u307e\u3059\u3002\u7537\u6027\uff08\u4e0a\u306e\u30b0\u30e9\u30d5\uff09\u3067\u306f1.9mmol\/L\uff0873mg\/dL\uff09\u3001\u5973\u6027\uff08\u4e0b\u306e\u30b0\u30e9\u30d5\uff09\u3067\u306f2.4mmol\/L\uff0893mg\/dL\uff09\u3067\u6700\u3082\u6b7b\u4ea1\u7387\u304c\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u305d\u306e\u30ec\u30d9\u30eb\u307e\u3067\u306fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u307b\u3069\u3001\u6b7b\u4ea1\u7387\u306f\u4f4e\u304f\u306a\u308b\u306e\u3067\u3059\u304c\u3001\u305d\u308c\u4ee5\u4e0a\u306b\u306a\u308b\u3068\u6b7b\u4ea1\u7387\u306f\u4e0a\u6607\u306b\u8ee2\u3058\u3066\u3057\u307e\u3046\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u5973\u6027\u306e\u30b0\u30e9\u30d5\u3092\u898b\u308b\u3068\u3001\u305d\u306e\u4e0a\u6607\u306e\u4ed5\u65b9\u306f\u975e\u5e38\u306b\u306a\u3060\u3089\u304b\u3067\u3059\u3002\u307e\u305f\u3001\u7537\u5973\u3068\u3068\u3082\u306b\u305d\u308c\u3050\u3089\u3044\u9ad8\u3044HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306b\u306a\u308b\u3068\u3001\u5bfe\u8c61\u306e\u4eba\u6570\u304c\u975e\u5e38\u306b\u5c11\u306a\u304f\u3001\u7cbe\u5ea6\u306b\u7591\u554f\u304c\u6b8b\u308a\u307e\u3059\u3002\u7537\u6027\u3067HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c100mg\/dL\u3092\u8d85\u3048\u308b\u4eba\u306f\u307b\u3068\u3093\u3069\u3044\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e0a\u306e\u56f3\u306f\u539f\u56e0\u5225\u306e\u6b7b\u4ea1\u7387\u3067\u3059\u304c\u3001\u4e0a\u304c\u7537\u6027\u3001\u4e0b\u304c\u5973\u6027\u3001\u5de6\u304b\u3089\u9806\u306b\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u3001\u304c\u3093\u3001\u305d\u306e\u4ed6\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u3067\u306f\u7537\u5973\u3068\u3082\u5b8c\u5168\u306b\u300cU\u5b57\u300d\u3092\u63cf\u3044\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3069\u306e\u539f\u56e0\u306b\u304a\u3044\u3066\u3082\u5973\u6027\u306e\u65b9\u304c\u30ab\u30fc\u30d6\u306f\u306a\u3060\u3089\u304b\u3067\u3059\u3002\u304c\u3093\u6b7b\u4ea1\u7387\u306b\u3064\u3044\u3066\u306f\u3001\u4f4e\u3044HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3001\u7537\u5973\u306b\u304a\u3044\u3066\u9ad8\u3044\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u9ad8\u3044HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3068\u306e\u95a2\u9023\u6027\u8a8d\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u305d\u306e\u4ed6\u306e\u6b7b\u4ea1\u306f\u3001\u7537\u6027\u3067\u306fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306eU\u5b57\u306e\u95a2\u9023\u3092\u793a\u3057\u307e\u3057\u305f\u304c\u3001\u5973\u6027\u3067\u306f\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u5fc3\u8840\u7ba1\u7cfb\u306e\u4e2d\u8eab\u5225\u3067\u3001\u4e0a\u306e\u30b0\u30e9\u30d5\u3067\u5de6\u304b\u3089\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u865a\u8840\u6027\u306e\u8133\u5352\u4e2d\uff08\u8133\u6897\u585e\uff09\u3092\u3042\u3089\u308f\u3057\u3066\u3044\u307e\u3059\u3002\u3069\u308c\u3082\u540c\u3058\u3088\u3046\u306a\u50be\u5411\u3067\u3042\u308a\u3001\u4f4e\u3044HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306b\u3064\u3044\u3066\u9ad8\u3044\u30ea\u30b9\u30af\u304c\u8a8d\u3081\u3089\u308c\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u7537\u6027\u30671.5mmol\/L\uff0858mg\/dL\uff09\u3001\u5973\u6027\u30672.0mmol\/L\uff0877mg\/dL\uff09\u307e\u3067\u306f\u30ea\u30b9\u30af\u306f\u4f4e\u4e0b\u3057\u3001\u305d\u308c\u4ee5\u4e0a\u9ad8\u304f\u3066\u3082\u30ea\u30b9\u30af\u306f\u4f4e\u4e0b\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u9006\u306b\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3082\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3064\u307e\u308a\u3001\u6975\u7aef\u306b\u9ad8\u3044HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306e\u6709\u610f\u306a\u5897\u52a0\u306f\u89b3\u5bdf\u3055\u308c\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u3002<\/p>\n

HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u6975\u7aef\u306b\u9ad8\u3044\u5834\u5408\u3001\u30b3\u30ec\u30b9\u30c6\u30ea\u30eb\u30a8\u30b9\u30c6\u30eb\u8ee2\u9001\u86cb\u767d\uff08CETP\uff09\u6b20\u640d\u75c7\u3068\u3044\u3046\u907a\u4f1d\u7684\u306a\u75c5\u6c17\u306e\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u30db\u30e2\u63a5\u5408\u4f53\uff08\u4e21\u65b9\u306e\u907a\u4f1d\u5b50\u304c\u3053\u306e\u75be\u60a3\u306e\u907a\u4f1d\u5b50\u306e\u5834\u5408\uff09\u304c\u6570\u4e07\u4eba\u306b\u4e00\u4eba\u3068\u8a00\u308f\u308c\u3066\u3044\u3066\u3001\u305d\u306e\u5834\u5408HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u6975\u7aef\u306b\u9ad8\u304f\u3001150\uff5e250mg\/dL\u306b\u306a\u308b\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3067\u3059\u304b\u3089\u3001\u6975\u7aef\u306b\u9ad8\u3044\u3068\u3044\u3063\u3066\u3082\u3001100\u7a0b\u5ea6\u306a\u3089\u3001\u6050\u3089\u304f\u306f\u3053\u306e\u75be\u60a3\u3067\u306f\u306a\u3044\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u601d\u3044\u307e\u3059\u3002\uff08\u907a\u4f1d\u5b50\u306e\u7247\u65b9\u3060\u3051\u306e\u30d8\u30c6\u30ed\u306e\u5834\u5408\u306f\u305d\u3093\u306a\u306b\u9ad8\u304f\u306f\u306a\u3089\u306a\u3044\u3088\u3046\u3067\u3059\u304c\uff09<\/p>\n

\u4ee5\u524d\u306e\u8a18\u4e8b\u3067\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u5897\u52a0\u3068\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u306f\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3068\u4e2d\u6027\u8102\u80aa\u5024\u306f\u9006\u306e\u76f8\u95a2\u304c\u3042\u308a\u307e\u3059\u3002\u4eca\u56de\u306e\u7814\u7a76\u5bfe\u8c61\u306e\u7537\u6027\u306e\u4e2d\u6027\u8102\u80aa\u306e\u5e73\u5747\u304c143mg\/dL\u3001\u5973\u6027\u304c108mg\/dL\u3067\u3042\u308b\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u7537\u6027\u3067\u306f\u6975\u7aef\u306bHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u3053\u3068\u306f\u53ef\u80fd\u6027\u304c\u4f4e\u304f\u3001\u5b9f\u969b\u306b\u5973\u6027\u3088\u308a\u5168\u4f53\u7684\u306b\u4f4e\u3044\u5024\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u3044\u72b6\u6cc1\u3067\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u5f71\u97ff\u304b\u3001\u307e\u305f\u306f\u5148\u307b\u3069\u306e\u30b3\u30ec\u30b9\u30c6\u30ea\u30eb\u30a8\u30b9\u30c6\u30eb\u8ee2\u9001\u86cb\u767d\uff08CETP\uff09\u6b20\u640d\u75c7\u306e\u7591\u3044\u304c\u3042\u308b\u304b\u3001\u3068\u601d\u308f\u308c\u307e\u3059\u3002\u305f\u3060\u3001\u4e2d\u6027\u8102\u80aa\u3084\u30a2\u30eb\u30b3\u30fc\u30eb\u306a\u3069\u3092\u8abf\u6574\u3057\u3066\u3082\u7537\u6027\u3067\u306fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u6975\u7aef\u306b\u9ad8\u3044\u3068\u6b7b\u4ea1\u7387\u304c\u9ad8\u304f\u306a\u308b\u3068\u3044\u3046\u306e\u306f\u5909\u308f\u3063\u3066\u3044\u307e\u305b\u3093\u3002\uff08\u4e0b\u306e\u56f3\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u771f\u3093\u4e2d\u306e\u56f3\u304c\u4e2d\u6027\u8102\u80aa\u3067\u8abf\u6574\u3055\u308c\u3066\u3044\u3066\u3001\u53f3\u5074\u304c\u591a\u56e0\u5b50\u3092\u8abf\u6574\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u591a\u56e0\u5b50\u8abf\u6574\u306e\u5973\u6027\u306e\u30b0\u30e9\u30d5\u3067\u306f\u307b\u3068\u3093\u3069HDL\u304c\u6975\u7aef\u306b\u9ad8\u304f\u3066\u3082\u30ea\u30b9\u30af\u306e\u4e0a\u6607\u306f\u5c11\u306a\u3044\u3067\u3059\u3002<\/p>\n

\u305d\u3046\u3059\u308b\u3068\u3001\u5fc5\u305a\u3057\u3082HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u6975\u7aef\u306b\u9ad8\u3044\u3068\u3044\u3046\u3060\u3051\u3067\u3001\u6b7b\u4ea1\u7387\u304c\u9ad8\u304f\u306a\u308b\u3068\u3044\u3046\u306e\u3082\u5973\u6027\u3067\u306f\u3042\u307e\u308a\u8003\u3048\u308b\u5fc5\u8981\u306f\u306a\u3044\u3068\u601d\u308f\u308c\u307e\u3059\u3002\u7537\u6027\u306e\u5834\u5408\u306f\u95a2\u9023\u306f\u5426\u5b9a\u3067\u304d\u307e\u305b\u3093\u3002\u307e\u305f\u3001\u9006\u306bHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c40\u672a\u6e80\u306e\u4f4e\u5024\u306f\u7537\u5973\u3068\u3082\u975e\u5e38\u306b\u5371\u967a\u3067\u3042\u308a\u3001\u5973\u6027\u306f\u3082\u3046\u5c11\u3057\u9ad8\u3044\u65b9\u304c\u5b89\u5168\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u3055\u3089\u306b\u3001\u85ac\u3084\u30ca\u30a4\u30a2\u30b7\u30f3\u306e\u4f7f\u7528\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u3067HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u304f\u306a\u3063\u3066\u3082\u3001\u3082\u3057\u304b\u3057\u305f\u3089\u3001\u8cea\u306e\u60aa\u3044HDL\u3060\u3051\u304c\u5897\u52a0\u3057\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u305d\u3057\u3066\u3055\u3089\u306b\u3001\u3053\u308c\u304c\u4e00\u756a\u5927\u4e8b\u3067\u3059\u304c\u3001\u3053\u306e\u7814\u7a76\u306f\u3042\u304f\u307e\u3067\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306e\u4eba\u304c\u307b\u3068\u3093\u3069\u3092\u5360\u3081\u305f\u7814\u7a76\u3067\u3042\u308a\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3057\u305f\u5834\u5408\u306e\u30c7\u30fc\u30bf\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7cd6\u8cea\u5236\u9650\u3067HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u5897\u52a0\u3059\u308b\u306e\u3067\u3059\u304c\u3001\u3053\u306e\u5897\u52a0\u3057\u305fHDL\u306e\u8cea\u306f\u5b9f\u969b\u306b\u306f\u308f\u304b\u3089\u306a\u3044\u306e\u304c\u73fe\u5b9f\u3067\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5897\u52a0\u3068\u5171\u306b\u3001\u4e2d\u6027\u8102\u80aa\u304c\u975e\u5e38\u306b\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u591a\u3044\u306e\u3067\u3001\u79c1\u306f\u8cea\u306e\u826f\u3044HDL\u304c\u5897\u52a0\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4eca\u5ea6\u3001\u8cea\u306b\u95a2\u3057\u3066\u8a18\u4e8b\u306b\u3059\u308b\u3064\u3082\u308a\u3067\u3059\u3002<\/p>\n

 <\/p>\n

\u300cExtreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies\u300d<\/span><\/p>\n

\u300c\u6975\u7aef\u306b\u9ad8\u3044HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3001\u7537\u6027\u304a\u3088\u3073\u5973\u6027\u306b\u304a\u3051\u308b\u9ad8\u3044\u6b7b\u4ea1\u7387\u3068\u9006\u8aac\u7684\u306b\u95a2\u9023\u3059\u308b\uff1a2\u3064\u306e\u524d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u300d\uff08\u539f\u6587\u306f\u3053\u3053<\/a>\uff09<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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