{"id":3967,"date":"2018-04-02T07:15:56","date_gmt":"2018-04-01T22:15:56","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=3967"},"modified":"2020-01-10T08:44:53","modified_gmt":"2020-01-09T23:44:53","slug":"post-3967","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=3967","title":{"rendered":"HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u9ad8\u3051\u308c\u3070\u826f\u3044\u3063\u3066\u3082\u3093\u3058\u3083\u306a\u3044\uff1f\u3000\u305d\u306e4"},"content":{"rendered":"<p>\u901a\u5e38\u306fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u65b9\u304c\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>HDL\u306b\u306f\u69d8\u3005\u306a\u6a5f\u80fd\u304c\u3042\u308a\u307e\u3059\u3002\u5185\u76ae\u6a5f\u80fd\u6539\u5584\u4f5c\u7528\u3001\u6297\u9178\u5316\u4f5c\u7528\u3001\u6297\u708e\u75c7\u4f5c\u7528\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u9006\u8ee2\u9001\uff08\u8f38\u9001\uff09\u4f5c\u7528\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u6a5f\u80fd\u306b\u3088\u308a\u3001HDL\u306f\u6297\u52d5\u8108\u786c\u5316\u4f5c\u7528\u3092\u793a\u3059\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>HDL\u306b\u5099\u308f\u3063\u3066\u3044\u308b\u3053\u308c\u3089\u306e\u6a5f\u80fd\u306e\u3046\u3061\u3001\u3082\u3063\u3068\u3082\u5927\u5207\u306a\u306e\u306f\u3001\u52d5\u8108\u786c\u5316\u304c\u8d77\u304d\u3066\u3044\u308b\u90e8\u4f4d\uff08\u30d7\u30e9\u30fc\u30af\uff09\u306b\u5b58\u5728\u3059\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306a\u3069\u306e\u7d30\u80de\u304b\u3089\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u5f15\u304d\u629c\u3044\u3066\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u9006\u8ee2\u9001\u3057\u3001\u809d\u81d3\u306b\u904b\u3093\u3067\u80c6\u6c41\u3088\u308a\u4fbf\u306b\u6392\u6cc4\u3059\u308b\u50cd\u304d\u3067\u3059\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001\u3044\u304f\u3089HDL\u304c\u591a\u304f\u3066\u3082HDL\u306e\u8cea\u3001\u6a5f\u80fd\u304c\u60aa\u304f\u3001\u3053\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u9006\u8ee2\u9001\u4f5c\u7528\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308c\u3070\u3069\u3046\u3057\u3088\u3046\u3082\u306a\u3044\u308f\u3051\u3067\u3059\u3002<\/p>\n<p>\u305d\u306eHDL\u306e\u6a5f\u80fd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3072\u3068\u3064\u304c\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306eapoC\u2162\u3067\u3059\u3002\u3053\u308c\u306f\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=3546\" target=\"_blank\" rel=\"noopener noreferrer\">LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u672c\u5f53\u306b\u52d5\u8108\u306e\u8840\u7ba1\u5185\u8154\u304b\u3089\u8840\u7ba1\u5185\u76ae\u3092\u901a\u3063\u3066\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u3092\u8d77\u3053\u3059\u306e\u304b\uff1f\u3000\u305d\u306e5<\/a>\u300d\u306b\u3082\u767b\u5834\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u3088\u308a\u5c0f\u3055\u3044\u3001\u3088\u308a\u5bc6\u5ea6\u306e\u9ad8\u3044LDL\u7c92\u5b50\u306f\u30011\u7c92\u5b50\u3042\u305f\u308a\u3088\u308a\u591a\u304f\u306e\u91cf\u306eapoC\u2162\u3092\u6301\u3063\u3066\u3044\u3066\u3001\u30d3\u30b0\u30ea\u30ab\u30f3\u3068\u306e\u7d50\u5408\u80fd\u3082\u9ad8\u304f\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u3092\u8d77\u3053\u3057\u3084\u3059\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>apoC\u2162\u3092\u542b\u3080HDL\u306b\u3082\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u3002apoC\u2162\u306fHDL\u4ee5\u5916\u306b\u4e2d\u6027\u8102\u80aa\u304c\u8c4a\u5bcc\u306a\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u3084VLDL\u3001LDL\u306b\u3082\u5b58\u5728\u3057\u307e\u3059\u3002HDL\u306b\u542b\u307e\u308c\u308bapoC\u2162\u306e\u5272\u5408\u304c\u9ad8\u3044\u3068\u51a0\u52d5\u8108\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1.jpg\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"3969\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=3969\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1.jpg\" data-orig-size=\"675,464\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"apoc3HDL-1\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1.jpg\" class=\"alignnone size-medium wp-image-3969\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1-300x206.jpg\" alt=\"\" width=\"300\" height=\"206\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1-300x206.jpg 300w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1-320x220.jpg 320w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-1.jpg 675w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09HDL\u306b\u542b\u307e\u308c\u308bapoC\u2162\u306e\u5272\u5408\u306e\u56f3\u3067\u3059\u3002\u5de6\u306e\u9ed2\u3044\u30d0\u30fc\u304c\u51a0\u52d5\u8108\u75be\u60a3\u306e\u7fa4\u3001\u53f3\u306e\u30b0\u30ec\u30fc\u306e\u30d0\u30fc\u304c\u975e\u51a0\u52d5\u8108\u75be\u60a3\u306e\u7fa4\u3067\u3059\u3002\u660e\u3089\u304b\u306b\u51a0\u52d5\u8108\u75be\u60a3\u306e\u7fa4\u306e\u65b9\u304cHDL\u306b\u542b\u307e\u308c\u308bapoC\u2162\u306e\u5272\u5408\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u30b9\u30bf\u30c1\u30f3\u3092\u4f7f\u3063\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3001\u7cd6\u5c3f\u75c5\u304b\u3069\u3046\u304b\u3001\u55ab\u7159\u8005\u304b\u3069\u3046\u304b\u3068\u3044\u3046\u306e\u306f\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2.jpg\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"3970\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=3970\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2.jpg\" data-orig-size=\"675,480\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"apoc3HDL-2\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2.jpg\" class=\"alignnone size-medium wp-image-3970\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2-300x213.jpg\" alt=\"\" width=\"300\" height=\"213\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2-300x213.jpg 300w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2-320x228.jpg 320w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-2.jpg 675w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u5f15\u304d\u629c\u304f\u80fd\u529b\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u660e\u3089\u304b\u306b\u975e\u51a0\u52d5\u8108\u75be\u60a3\u306e\u7fa4\u3067\u5f15\u304d\u629c\u304d\u80fd\u306f\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3.jpg\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"3971\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=3971\" data-orig-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3.jpg\" data-orig-size=\"675,479\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"apoc3HDL-3\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3.jpg\" class=\"alignnone size-medium wp-image-3971\" src=\"http:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3-300x213.jpg\" alt=\"\" width=\"300\" height=\"213\" srcset=\"https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3-300x213.jpg 300w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3-320x227.jpg 320w, https:\/\/promea2014.com\/blog\/wp-content\/uploads\/2018\/03\/apoc3HDL-3.jpg 675w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>HDL\u306b\u542b\u307e\u308c\u308bapoC\u2162\u306e\u5272\u5408\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5f15\u304d\u629c\u304d\u80fd\u306f\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3001\u3082\u306e\u3059\u3054\u304f\u9055\u3046\u304b\u3068\u3044\u3046\u3068\u305d\u3046\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u9055\u3044\u304c\u52d5\u8108\u786c\u5316\u306b\u5927\u304d\u306a\u9055\u3044\u3092\u751f\u3080\u306e\u304b\u306f\u79c1\u306b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u307e\u305f\u3001apoC\u2162\u306f\u4e2d\u6027\u8102\u80aa\u304c\u591a\u3044\u3068\u5897\u52a0\u3059\u308b\u306e\u3067\u3001\u4e2d\u6027\u8102\u80aa\u5024\u304c\u9ad8\u3044\u3068\u51a0\u52d5\u8108\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u306e\u3082\u7d0d\u5f97\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u5225\u306e\u7814\u7a76\u3067\u306f\u51a0\u52d5\u8108\u75be\u60a3\u306e\u60a3\u8005\u306b\u304a\u3051\u308b\u30b9\u30bf\u30c1\u30f3\u306b\u3088\u308b\u6cbb\u7642\u524d\u5f8c\u3067\u306e\u8102\u8cea\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u3092\u8abf\u3079\u305f\u3068\u3053\u308d\u3001HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f1.05mmol\/L\uff0840.6mg\/dl\uff09\u304b\u30891.21\uff0846.8mg\/dl\uff09\u306b\u5897\u52a0\u3057\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306f2.84mmol\/L\uff08109.8mg\/dl\uff09\u304b\u30892.19\uff0884.7mg\/dl\uff09\u306b\u6e1b\u5c11\u3057\u305f\u306e\u3067\u3059\u304c\u3001HDL\u306b\u542b\u307e\u308c\u308bapoC\u2162\u306f\u9006\u306b24.26(ug\/mgHDL)\u304b\u308929.35\u306b\u5897\u52a0\u3057\u3066\u3057\u307e\u3044\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u666e\u901a\u306b\u8003\u3048\u308b\u306a\u3089\u3070\u3001\u30b9\u30bf\u30c1\u30f3\u306b\u3088\u3063\u3066\u5897\u52a0\u3057\u305fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u6a5f\u80fd\u4e0d\u5168\u306eapoC\u2162\u3092\u8c4a\u5bcc\u306b\u542b\u3093\u3060HDL\u304c\u5897\u3048\u305f\u3060\u3051\u3067\u3059\u3002<\/p>\n<p>\u3064\u307e\u308a\u3001\u3044\u304f\u3089HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u5897\u52a0\u3057\u3066\u3082\u3001\u6a5f\u80fd\u4e0d\u5168\u306eHDL\u304c\u5897\u3048\u305f\u306a\u3089\u3070\u3001\u610f\u5473\u304c\u306a\u3044\u308f\u3051\u3067\u3059\u3002\u3084\u306f\u308a\u305d\u3053\u3067\u8003\u3048\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u306f\u4e2d\u6027\u8102\u80aa\u5024\u3067\u3057\u3087\u3046\u3002\u4e2d\u6027\u8102\u80aa\u5024\u304c\u975e\u5e38\u306b\u9ad8\u3044\u72b6\u614b\u3067\u306eHDL\u5897\u52a0\u306f\u8cea\u306e\u60aa\u3044HDL\u5897\u52a0\u3060\u3068\u8003\u3048\u308b\u65b9\u304c\u59a5\u5f53\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u7cd6\u8cea\u5236\u9650\u3092\u3057\u3066\u3001\u4e2d\u6027\u8102\u80aa\u306f100\u4ee5\u4e0b\u3092\u76ee\u6307\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\">\u300cApoCIII enrichment in HDL impairs HDL-mediated cholesterol efflux capacity\u300d<\/span><\/p>\n<p><span style=\"color: #0000ff;\">\u300cHDL\u306b\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u308bapoC\u2162\u306f\u3001HDL\u306b\u3088\u308b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5f15\u304d\u629c\u304d\u80fd\u529b\u3092\u640d\u306a\u3046\u300d\uff08\u539f\u6587\u306f<a style=\"color: #0000ff;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28539597\" target=\"_blank\" rel=\"noopener noreferrer\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u901a\u5e38\u306fHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u65b9\u304c\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 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