{"id":426,"date":"2016-02-22T10:41:35","date_gmt":"2016-02-22T01:41:35","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=426"},"modified":"2016-09-07T13:57:11","modified_gmt":"2016-09-07T04:57:11","slug":"post-426","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=426","title":{"rendered":"\u9006\u6d41\u6027\u98df\u9053\u708e\u3068\u8a8d\u77e5\u75c7"},"content":{"rendered":"

Medical Tribune\u306b\u8208\u5473\u6df1\u3044\u8a71\u304c\u51fa\u3066\u3044\u305f\u306e\u3067\u3001\u629c\u7c8b\u3057\u307e\u3057\u305f\u3002<\/span><\/p>\n

\u9006\u6d41\u6027\u98df\u9053\u708e\u306e\u85ac\u3067\u3042\u308b\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u4eba\u306f\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u304c1.4\u500d\u306b\u306a\u308b\u3068\u3044\u3046\u30c7\u30fc\u30bf\u3067\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u3053\u308c\u306f\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\u3068\u3044\u3046\u85ac\u304c\u60aa\u3044\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u9006\u6d41\u6027\u98df\u9053\u708e\u3092\u8d77\u3053\u3059\u5143\u3005\u306e\u98df\u7fd2\u6163\u304c\u60aa\u3044\u306e\u304b<\/p>\n

\u3069\u3063\u3061\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\u3092\u9577\u671f\u9593\u98f2\u3093\u3067\u3044\u308b\u3068\u3001\u30d3\u30bf\u30df\u30f3B12\u304c\u4e0d\u8db3\u3057\u3066\u8a8d\u77e5\u75c7\u69d8\u306e\u75c7\u72b6\u304c\u51fa\u308b\u3053\u3068\u306f\u4ee5\u524d\u304b\u3089\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u307e\u305f\u3001\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u3068\u9006\u6d41\u6027\u98df\u9053\u708e\u304c\u8457\u660e\u306b\u6539\u5584\u3059\u308b\u3044\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

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\u3064\u307e\u308a\u3001\u9006\u6d41\u6027\u98df\u9053\u708e\u3092\u8d77\u3053\u3059\u65b9\u306f\u5143\u3005\u7cd6\u8cea\u6442\u53d6\u304c\u904e\u591a\u3067\u3042\u308a\u3001\u983b\u7e41\u306b\u98df\u5f8c\u9ad8\u8840\u7cd6\u3092\u8d77\u3053\u3057\u7d9a\u3051\u305f\u305f\u3081\u306b\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u3063\u305f\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n

\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001\u5bfe\u75c7\u7642\u6cd5\u3060\u3051\u3067\u9577\u671f\u9593\u904e\u3054\u3059\u3053\u3068\u306f\u554f\u984c\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u305d\u308c\u306f\u3069\u3093\u306a\u75c5\u6c17\u3067\u3082\u540c\u3058\u3067\u3059\u3002<\/p>\n

\u98df\u7fd2\u6163\u306e\u898b\u76f4\u3057\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n

 <\/p>\n

PPI\u4f7f\u7528\u3067\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u304c\u4e0a\u6607\uff1f<\/span><\/h1>\n

2016.02.18\u3000Medical Tribune<\/span><\/p>\n

\u3000\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff08PPI\uff09\u306e\u4f7f\u7528\u306f\u9ad8\u9f62\u8005\u3067\u5897\u3048\u3066\u3044\u308b\u304c\uff0c\u540c\u85ac\u304c\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306b\u95a2\u4fc2\u3059\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f\u5831\u544a\u3082\u3042\u308b\u3002\u30c9\u30a4\u30c4\u30fbGerman Center for Neurodegenerative Diseases\u306eBritta Haenisch\u6c0f\u3089\u306f\uff0c\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306b\u8a8d\u77e5\u75c7\u306e\u306a\u304475\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62PPI\u4f7f\u7528\u80057\u4e07\u4eba\u8d85\u306e\u5065\u5eb7\u4fdd\u967a\u30c7\u30fc\u30bf\u3092\u524d\u5411\u304d\u306b\u8ffd\u8de1\u3057\uff0c\u5bfe\u7167\u96c6\u56e3\u306e\u30c7\u30fc\u30bf\u3068\u6bd4\u8f03\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\uff0cPPI\u4f7f\u7528\u7fa4\u3067\u306f\uff0c\u975e\u4f7f\u7528\u7fa4\u306b\u6bd4\u3079\u3066\u8a8d\u77e5\u75c7\u767a\u75c7\u30ea\u30b9\u30af\u304c1.4\u500d\u6709\u610f\u306b\u9ad8\u304b\u3063\u305f\u3068JAMA Neurol<\/i>\u3067\u5831\u544a\u3057\u305f\u3002<\/span><\/p>\n

\n

\u5927\u898f\u6a21\u4fdd\u967a\u30c7\u30fc\u30bf\u3067\u524d\u5411\u304d\u8ffd\u8de1<\/span><\/h3>\n

\u80c3\u98df\u9053\u9006\u6d41\u75c7\uff08GERD\uff09\u3084\u80c3\u6f70\u760d\u306b\u5bfe\u3059\u308bPPI\u306e\u4f7f\u7528\u306f\uff0c\u9ad8\u9f62\u8005\u3092\u4e2d\u5fc3\u306b\u6025\u5897\u3057\u3066\u3044\u308b\u3002\u307e\u305f\uff0cPPI\u306f\u5168\u85ac\u5264\u3067\u898b\u3066\u3082\u6700\u3082\u591a\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u90e8\u985e\u306b\u5165\u308a\uff0c\u30c9\u30a4\u30c4\u3067\u306f\u904e\u53bb10\u5e74\u9593\u306b\u51e6\u65b9\u6570\u304c4\u500d\u306b\u5897\u3048\u305f\u3002\u305d\u306e\u51e6\u65b9\u306e40\uff5e60\uff05\u306f\u4e0d\u9069\u5207\u306a\u3082\u306e\u3060\u3068\u3059\u308b\u89b3\u5bdf\u7814\u7a76\u3082\u3042\u308b\u3002<\/span><\/p>\n

\u4e00\u65b9\u3067\uff0cPPI\u4f7f\u7528\u306f\u8a8d\u77e5\u6a5f\u80fd\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u304a\u308a\uff0c\u305d\u306e\u8981\u56e0\u3068\u3057\u3066\uff0cPPI\u4f7f\u7528\u3068\u30d3\u30bf\u30df\u30f3B12<\/sub>\u6b20\u4e4f\uff0c\u8133\u5185\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\uff08A\u03b2\uff09\u84c4\u7a4d\u3068\u306e\u95a2\u9023\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u308b\u3002<\/span><\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\uff0c\u30c9\u30a4\u30c4\u6700\u5927\u306e\u516c\u7684\u5065\u5eb7\u4fdd\u967a\u5236\u5ea6\uff08Allgemeine Ortskrankenkassen\uff09\u306e\u8a18\u9332\u306b\u304a\u3044\u3066\uff0c2004\uff5e11\u5e74\u306e\u5165\u9662\u304a\u3088\u3073\u5916\u6765\u60a3\u8005\u306e\u8a3a\u65ad\u8a18\u9332\u3068\u85ac\u5264\u51e6\u65b9\u30c7\u30fc\u30bf\u3092\u524d\u5411\u304d\u306b\u8ffd\u8de1\u3057\uff0cPPI\u306e\u4f7f\u7528\u3068\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u3092\u691c\u8a0e\u3057\u305f\u3002<\/span><\/p>\n

\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\uff0c\u56fd\u969b\u75be\u75c5\u5206\u985e\uff08ICD-10\uff09\u306e\u30c9\u30a4\u30c4\u7248\u306b\u3088\u308b\u8a8d\u77e5\u75c7\u767a\u75c7\u3068\u3057\uff0c\u6642\u9593\u4f9d\u5b58\u6027\u5171\u5909\u91cf\u3092\u7528\u3044\u305fCox\u56de\u5e30\u5206\u6790\u306b\u3088\u308a\uff0c\u5e74\u9f62\uff0c\u6027\uff0c\u4f75\u5b58\u75be\u60a3\uff0c\u591a\u5264\u670d\u7528\u306a\u3069\u306e\u4ea4\u7d61\u56e0\u5b50\u3092\u8abf\u6574\u3057\uff0cPPI\u4f7f\u7528\u3068\u8a8d\u77e5\u75c7\u306e\u95a2\u9023\u3092\u691c\u8a0e\u3057\u305f\u3002<\/span><\/p>\n

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\u9ad8\u9f62\u8005\u304c\u5e38\u7528\u3059\u308b\u85ac\u5264\u306b\u3064\u3044\u3066\u306e\u91cd\u8981\u306a\u554f\u984c\u63d0\u8d77<\/span><\/h3>\n

7\u4e073,679\u4eba\u306e\u3046\u3061\uff0cPPI\u5b9a\u671f\u4f7f\u7528\u306f2,950\u4eba\uff08\u5973\u602777.9\uff05\uff0c\u5e73\u5747\u5e74\u9f6283.8\u6b73\uff09\u3067\uff0c\u975e\u4f7f\u7528\u8005\u306f7\u4e07729\u4eba\uff08\u5973\u602773.6\uff05\uff0c\u5e73\u5747\u5e74\u9f6283.0\u6b73\uff09\u3067\u3042\u3063\u305f\u3002\u8ffd\u8de1\u671f\u9593\u4e2d\u306b\u8a8d\u77e5\u75c7\u3092\u767a\u75c7\u3057\u305f\u306e\u306f\uff0c\u5168\u4f53\u30672\u4e079,510\u4eba\u3067\uff0cPPI\u5b9a\u671f\u4f7f\u7528\u7fa4\u306e\u8a8d\u77e5\u75c7\u767a\u75c7\u30ea\u30b9\u30af\u306f\uff0c\u975e\u4f7f\u7528\u7fa4\u3068\u6bd4\u3079\u6709\u610f\u306b\u9ad8\u304b\u3063\u305f\uff08\u30cf\u30b6\u30fc\u30c9\u6bd41.44\uff0c95\uff05CI 1.36\uff5e1.52\uff0cP\uff1c0.001\uff09\u3002<\/span><\/p>\n

Haenisch\u6c0f\u3089\u306f\u300c\u4eca\u56de\u306e\u7814\u7a76\u306f\uff0c\u904e\u53bb\u306e\u85ac\u5264\u75ab\u5b66\u30c7\u30fc\u30bf\u3084\u52d5\u7269\u5b9f\u9a13\u306e\u7d50\u679c\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u3067\uff0cPPI\u4f7f\u7528\u306e\u56de\u907f\u3067\u8a8d\u77e5\u75c7\u767a\u75c7\u3092\u4e88\u9632\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u300d\u3068\u6307\u6458\u3002\u4e00\u65b9\u3067\uff0c\u4eca\u56de\u306e\u7814\u7a76\u306fPPI\u4f7f\u7528\u3068\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u751f\u7269\u5b66\u7684\u56e0\u679c\u95a2\u4fc2\u3092\u8a3c\u660e\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3053\u3068\u3084\uff0c\u65e2\u77e5\u306e\u8a8d\u77e5\u75c7\u5371\u967a\u56e0\u5b50\u306e\u3046\u3061\u8abf\u6574\u3067\u304d\u306a\u304b\u3063\u305f\u3082\u306e\u3082\u3042\u308b\u3053\u3068\u306b\u8a00\u53ca\u3002\u300c\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308bPPI\u4f7f\u7528\u3068\u8a8d\u77e5\u75c7\u767a\u75c7\u306b\u95a2\u3057\u3066\uff0c\u76f4\u63a5\u7684\u306a\u56e0\u679c\u95a2\u4fc2\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u306f\uff0c\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u304c\u5fc5\u8981\u3067\u3042\u308b\u300d\u3068\u7d50\u8ad6\u4ed8\u3051\u3066\u3044\u308b\u3002<\/span><\/p>\n

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