{"id":4444,"date":"2018-06-05T06:36:35","date_gmt":"2018-06-04T21:36:35","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=4444"},"modified":"2020-01-10T08:40:27","modified_gmt":"2020-01-09T23:40:27","slug":"post-4444","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=4444","title":{"rendered":"LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u672c\u5f53\u306b\u52d5\u8108\u306e\u8840\u7ba1\u5185\u8154\u304b\u3089\u8840\u7ba1\u5185\u76ae\u3092\u901a\u3063\u3066\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u3092\u8d77\u3053\u3059\u306e\u304b\uff1f\u3000\u305d\u306e7\u3000\u9178\u5316LDL\u3092\u72af\u4eba\u3068\u8003\u3048\u308b\u524d\u306b"},"content":{"rendered":"

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\u3057\u304b\u3057\u3001\u9178\u5316LDL\u306fLDL\u306e0.1\uff05\u4ee5\u4e0b\u3060\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3082\u6e2c\u5b9a\u6cd5\u306e\u554f\u984c\u3082\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001LDL\u306e\u6570\uff05\u304csdLDL\u3067\u305d\u306esdLDL\u306e\u6570\uff05\u304c\u9178\u5316LDL\u3067\u3059\u3002\u304b\u306a\u308a\u306e\u5fae\u91cf\u3067\u3059\u3002\u305d\u3093\u306a\u5fae\u91cf\u306e\u3082\u306e\u304c\u679c\u305f\u3057\u3066\u30a2\u30c6\u30ed\u30fc\u30e0\u3092\u4f5c\u308a\u51fa\u3059\u539f\u56e0\u306a\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u4eba\u9593\u306e\u9632\u5fa1\u6a5f\u80fd\u304c\u305d\u3053\u307e\u3067\u60aa\u3044\u3068\u306f\u601d\u3048\u307e\u305b\u3093\u3002\u5b9f\u969b\u306b\u3053\u306e\u8840\u4e2d\u306e\u5fae\u91cf\u306a\u9178\u5316LDL\u306e\u6fc3\u5ea6\u3067\u306f\u3001\u5b9f\u9a13\u4e0a\u306e\u751f\u7406\u6d3b\u6027\u3092\u793a\u3059\u6fc3\u5ea6\u306e100\u5206\u306e1\u4ee5\u4e0b\u3067\u3042\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305d\u3053\u3067\u3001\u3082\u3046\u4e00\u5ea6\u57fa\u672c\uff08\uff1f\uff09\u306b\u7acb\u3061\u304b\u3048\u3063\u3066\u307f\u307e\u3059\u3002\u6211\u3005\u306f\u7cd6\u8cea\u5236\u9650\u304c\u4eba\u9593\u306e\u672c\u6765\u306e\u98df\u4e8b\u3067\u3042\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u73fe\u5728\u306e\u98df\u4e8b\u3067\u60aa\u3044\u306e\u306f\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3067\u3059\u3002\u3064\u307e\u308a\u9ad8\u8840\u7cd6\u306b\u306a\u308b\u3053\u3068\u304c\u5927\u304d\u306a\u5143\u306e\u539f\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002\u305d\u3046\u8003\u3048\u308b\u3068\u3001\u305d\u306e\u5f8c\u306b\u6765\u308b\u73fe\u8c61\u306f\u300c\u7cd6\u5316\u300d\u3067\u3059\u3002<\/p>\n

\u3064\u307e\u308a\u3001\u9178\u5316LDL\u306e\u524d\u306b\u8003\u3048\u308b\u3079\u304d\u306f\u300c\u7cd6\u5316LDL\u300d\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3044\u307e\u3059\u3002\u9ad8\u8840\u7cd6\u306f\u69d8\u3005\u306a\u3082\u306e\u3092\u7cd6\u5316\u3057\u307e\u3059\u3002\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u3082\u5f53\u7136\u7cd6\u5316\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u7cd6\u5316LDL\u306f\u6050\u3089\u304f\u9178\u5316LDL\u3068\u540c\u3058\u3088\u3046\u306a\u6d3b\u6027\u304c\u3042\u308a\u3001\u7cd6\u5316HDL\u306f\u6a5f\u80fd\u4e0d\u5168\u3068\u306a\u308a\u3001\u7cd6\u5316VLDL\u306f\u30ec\u30e0\u30ca\u30f3\u30c8\u306b\u306a\u308b\u306e\u3067\u3059\u3002<\/p>\n

\u8840\u4e2d\u3067\u306a\u304f\u3066\u3082\u5f53\u7136\u3001\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\uff08\u7d30\u80de\u3068\u7d30\u80de\u306e\u9593\u3092\u57cb\u3081\u3066\u3044\u308b\u975e\u5e38\u306b\u91cd\u8981\u306a\u69cb\u9020\u30fb\u7269\u8cea\uff09\u3082\u7cd6\u3067\u3044\u3063\u3071\u3044\u306b\u306a\u308b\u306f\u305a\u3067\u3059\u3002\u5185\u819c\u306e\u6df1\u5c64\u3067\u30d3\u30b0\u30ea\u30ab\u30f3\u306b\u6355\u3089\u3048\u3089\u308c\u308b\u3068\u304d\u306b\u306fLDL\u306f\u3059\u3067\u306b\u7cd6\u5316\u3057\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u3092\u3057\u3066\u3044\u308b\u306e\u3067apoC\u2162\u3082\u591a\u304f\u306a\u308a\u3001\u30d3\u30b0\u30ea\u30ab\u30f3\u306b\u6355\u3089\u3048\u3089\u308c\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u307e\u305f\u3001AGE\u304c\u5897\u52a0\u3059\u308b\u3068\u6297\u9178\u5316\u7269\u8cea\u304c\u67af\u6e07\u3059\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u5185\u819c\u306e\u6df1\u5c64\u3067\u306f\u6297\u9178\u5316\u7269\u8cea\u3082\u6e1b\u5c11\u3057\u3001\u7cd6\u5316\u3057\u305fLDL\u306f\u3088\u308a\u9178\u5316\u3057\u3084\u3059\u304f\u306a\u308b\u306e\u3067\u3059\u3002<\/p>\n

\u3082\u3046\u4e00\u5ea6\u304a\u3055\u3089\u3044\u3057\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n

1\uff0e\u52d5\u8108\u306e\u5185\u819c\u306f\u8840\u7ba1\u304c\u306a\u304f\u3001\u8840\u7ba1\u306e\u5185\u8154\u304b\u3089\u672c\u6765\u306f\u8840\u6db2\u6210\u5206\u3084\u6804\u990a\u3092\u53d7\u3051\u53d6\u308b\u3002<\/p>\n

2\uff0e\u7cd6\u8cea\u904e\u5270\u72b6\u614b\u304c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u751f\u307f\u3001\u5185\u819c\u306e\u7d30\u80de\u304c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u969c\u5bb3\u306b\u306a\u308a\u3001\u305d\u308c\u306b\u3088\u308bMfn-2\u306e\u6e1b\u5c11\u306f\u8840\u7ba1\u5e73\u6ed1\u7b4b\u7d30\u80de\u306e\u5897\u6b96\u3092\u62db\u304f\u3002<\/p>\n

3\uff0e\u3055\u3089\u306b\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u305d\u306e\u3082\u306e\u3084\u305d\u308c\u306b\u3088\u3063\u3066\u4fc3\u9032\u3055\u308c\u308bTGF-\u03b21\u3001\u305d\u306e\u4ed6\u306e\u6210\u9577\u56e0\u5b50\u306b\u3088\u308a\u3001\u3055\u3089\u306b\u8840\u7ba1\u5e73\u6ed1\u7b4b\u7d30\u80de\u306e\u5897\u6b96\u80fd\u529b\u304c\u5f37\u5316\u3055\u308c\u3001\u5185\u819c\u304c\u3069\u3093\u3069\u3093\u80a5\u539a\u3059\u308b\u3002<\/p>\n

4\uff0e\u5185\u819c\u304c\u539a\u304f\u306a\u308b\u3053\u3068\u306b\u3088\u308a\u5185\u819c\u306e\u6df1\u5c64\u3067\u306f\u4f4e\u9178\u7d20\u72b6\u614b\u306b\u306a\u308b\u3002<\/p>\n

5\uff0e\u80a5\u539a\u3057\u305f\u5185\u819c\u306e\u6df1\u5c64\u90e8\u5206\u306b\u5916\u819c\u304b\u3089\u65b0\u751f\u8840\u7ba1\u304c\u4f38\u3073\u3066\u304f\u308b\u3002<\/p>\n

6\uff0e\u4f38\u3073\u305f\u8840\u7ba1\u3092\u901a\u308b\u8840\u6db2\u306e\u4e2d\u306e\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u5185\u819c\u306e\u6df1\u5c64\u90e8\u5206\u306b\u5b58\u5728\u3059\u308b\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u306e\u30d3\u30b0\u30ea\u30ab\u30f3\u306b\u63a5\u89e6\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u7d50\u5408\u3059\u308b\u3002<\/p>\n

7\uff0e\u4e00\u65b9\u3067\u3001\u5185\u819c\u306e\u5897\u6b96\u3057\u305f\u8840\u7ba1\u5e73\u6ed1\u7b4b\u7d30\u80de\u306f\u6a5f\u68b0\u7684\u306a\u6b6a\u307f\u306a\u3069\u4f55\u3089\u304b\u306e\u30b9\u30c8\u30ec\u30b9\u3067\u30d3\u30b0\u30ea\u30ab\u30f3\u3092\u5897\u52a0\u3055\u305b\u308b\u3002\u9ad8\u8840\u7cd6\u3001\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u305d\u306e\u3082\u306e\u3084\u3001\u305d\u308c\u306b\u3088\u308b\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u3063\u3066\u3082\u30d3\u30b0\u30ea\u30ab\u30f3\u306f\u5897\u52a0\u3059\u308b\u3002<\/p>\n

8\uff0e\u3082\u3068\u3082\u3068\u306e\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306e\u751f\u6d3b\u3067\u3042\u308c\u3070\u3001\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u304f\u3001LDL\u306f\u5c0f\u3055\u304f\u5bc6\u5ea6\u304c\u9ad8\u3044\u3082\u306e\u304c\u591a\u304f\u306a\u308a\u3001\u3055\u3089\u306bapoC\u2162\u3092\u6709\u3059\u308bLDL\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5897\u52a0\u3059\u308b\u3002<\/p>\n

9\uff0eVLDL\u3001LDL\u3001HDL\u306a\u3069\u306e\u5168\u3066\u306e\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u9ad8\u8840\u7cd6\u306b\u3088\u308a\u7cd6\u5316\u3059\u308b\u3002<\/p>\n

10\uff0eapoC\u2162\u304c\u5897\u52a0\u3057\u305f\u308a\u7cd6\u5316\u3057\u305f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u53d7\u5bb9\u4f53\u306b\u304f\u3063\u3064\u304d\u306b\u304f\u304f\u306a\u308b\u3053\u3068\u3068\u306b\u3088\u308a\u30ec\u30e0\u30ca\u30f3\u30c8\u304c\u5897\u52a0\u3059\u308b\u3002\u8840\u4e2d\u306b\u9577\u304f\u3068\u3069\u307e\u308b\u30ec\u30e0\u30ca\u30f3\u30c8\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3055\u3089\u306b\u7cd6\u5316\u3057\u3084\u3059\u304f\u306a\u308b\u3002<\/p>\n

11\uff0eapoC\u2162\u304c\u5897\u52a0\u3057\u305f\u308a\u7cd6\u5316\u3057\u305fHDL\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5f15\u304d\u629c\u304d\u80fd\u306a\u3069\u306e\u4f4e\u4e0b\u3001\u3064\u307e\u308a\u6a5f\u80fd\u4e0d\u5168\u306b\u9665\u308b\u3002<\/p>\n

12\uff0e\u7cd6\u5316\u3057\u305fLDL\u3084VLDL\u306a\u3069\u306e\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u5185\u819c\u6df1\u5c64\u90e8\u3067\u30d3\u30b0\u30ea\u30ab\u30f3\u306b\u7d50\u5408\u3057\u3084\u3059\u304f\u306a\u308a\u3001\u8102\u8cea\u304c\u84c4\u7a4d\u3059\u308b\u3053\u3068\u306b\u306a\u308b\u3002<\/p>\n

13\uff0e\u7cd6\u5316\u3057\u305f\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u9178\u5316\u3057\u3084\u3059\u304f\u306a\u308a\u3001\u5185\u819c\u6df1\u5c64\u90e8\u3067\u9178\u5316\u3057\u305fLDL\u304c\u5897\u52a0\u3059\u308b\u3002<\/p>\n

14\uff0e\u305d\u306e\u9178\u5316\u3057\u305fLDL\u306e\u4e00\u90e8\u304c\u5185\u819c\u306e\u6df1\u5c64\u90e8\u306e\u65b0\u751f\u8840\u7ba1\u304b\u3089\u8840\u4e2d\u306b\u6f0f\u308c\u51fa\u3066\u304f\u308b\u3002<\/p>\n

 <\/p>\n

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