{"id":4674,"date":"2018-06-19T05:09:10","date_gmt":"2018-06-18T20:09:10","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=4674"},"modified":"2020-01-10T08:44:14","modified_gmt":"2020-01-09T23:44:14","slug":"post-4674","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=4674","title":{"rendered":"\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u306f\u4fae\u308c\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u306a\u3044"},"content":{"rendered":"

\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u30ec\u30e0\u30ca\u30f3\u30c8\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u98df\u5f8c12\u6642\u9593\u7d4c\u3063\u3066\u3082\u5927\u91cf\u306b\u6b8b\u3063\u3066\u3044\u308b<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u7a7a\u8179\u6642\u3067\u3042\u3063\u3066\u3082\u76f8\u5f53\u91cf\u306e\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u304c\u6b8b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u5065\u5eb7\u306a\u4eba\u306b\u304a\u3051\u308b\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u4e2d\u6027\u8102\u80aa\u306e\u534a\u6e1b\u671f\u306f\u975e\u5e38\u306b\u77ed\u304f\u3001\u7d045\u5206\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u7c92\u5b50\u81ea\u4f53\u306e\u534a\u6e1b\u671f\u306f\u3001\u306a\u304b\u306a\u304b\u9069\u5207\u306a\u6e2c\u5b9a\u304c\u56f0\u96e3\u3067\u3042\u308b\u305f\u3081\u3001\u306f\u3063\u304d\u308a\u3057\u305f\u3053\u3068\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u30cf\u30fc\u30d1\u30fc\u751f\u5316\u5b66\u306b\u306f\u534a\u6e1b\u671f\u304c1\u6642\u9593\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u7c92\u5b50\u306e\u534a\u6e1b\u671f\u306f\u3001\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u4e2d\u6027\u8102\u80aa\u306e\u534a\u6e1b\u671f\u3088\u308a\u3082\u78ba\u304b\u306b\u9577\u304f\u3001\u975e\u5e38\u306b\u4e0d\u5747\u4e00\u3067\u3042\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n

\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u306f\u3001\u3082\u3068\u3082\u3068\u306e\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u5927\u304d\u3055\u304c\u975e\u5e38\u306b\u5927\u304d\u3044\u305f\u3081\u3001\u76f8\u5f53\u306a\u4e2d\u6027\u8102\u80aa\u3092\u5931\u3063\u305f\u5f8c\u3067\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001VLDL\u3068\u540c\u3058\u3088\u3046\u306a\u5927\u304d\u3055\u3067\u3042\u308b\u3053\u3068\u3082\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u305d\u3046\u3059\u308b\u3068\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u304c\u6d88\u3048\u308b\u306e\u3082\u3001\u5c11\u306a\u304f\u3068\u3082\u540c\u3058\u3088\u3046\u306a\u30b5\u30a4\u30ba\u306eVLDL\u7c92\u5b50\u3068\u540c\u3058\u3088\u3046\u306a\u9577\u3055\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u5f8c\u3082\u3060\u3093\u3060\u3093\u5c0f\u3055\u304f\u306f\u306a\u3063\u305f\u3068\u3057\u3066\u308212\u6642\u9593\u5f8c\u306e\u7a7a\u8179\u6642\u3067\u3082\u3001\u5065\u5eb7\u306a\u4eba\u3067\u3055\u3048\u304b\u306a\u308a\u306e\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u304c\u6b8b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u9ad8\u4e2d\u6027\u8102\u80aa\u3068\u4f4eHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u7fa4\u3067\u306f\u3001\u6b63\u5e38\u3068\u6bd4\u3079\u3066\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u7d0411\u500d\u3001\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u4e2d\u6027\u8102\u80aa\u306f\u7d046\u500d\u3068\u524d\u56de\u306e\u8a18\u4e8b\u3067\u306f\u66f8\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u4e0b\u306e\u7814\u7a76\u30c7\u30fc\u30bf\u306f\u5065\u5eb7\u306a\u65e5\u672c\u4eba\u7537\u6027\u306b\u8102\u80aa\u8ca0\u8377\u8a66\u9a13\u3092\u3057\u305f\u6642\u306e\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n0 hr<\/td>\n2 hr<\/td>\n4 hr<\/td>\n6 hr<\/td>\n<\/tr>\n
TC<\/td>\n208\u00b17<\/td>\n207\u00b16<\/td>\n209\u00b16<\/td>\n208\u00b15<\/td>\n<\/tr>\n
TG<\/td>\n101\u00b115<\/td>\n153\u00b118\u2020<\/sup><\/td>\n210\u00b131\u2020<\/sup><\/td>\n165\u00b133*<\/sup><\/td>\n<\/tr>\n
HDL-C<\/td>\n70\u00b16<\/td>\n70\u00b16<\/td>\n68\u00b16<\/td>\n68\u00b18<\/td>\n<\/tr>\n
LDL-C<\/td>\n121\u00b18<\/td>\n121\u00b19<\/td>\n118\u00b18*<\/sup><\/td>\n119\u00b17<\/td>\n<\/tr>\n
RLP-C<\/td>\n4.8\u00b10.5<\/td>\n6.6\u00b10.5\u2020<\/sup><\/td>\n8.2\u00b11.1\u2020<\/sup><\/td>\n8.0\u00b11.6*<\/sup><\/td>\n<\/tr>\n
RLP-TG<\/td>\n13\u00b12<\/td>\n58\u00b19\u2020<\/sup><\/td>\n100\u00b120\u2020<\/sup><\/td>\n69\u00b120\u2020<\/sup><\/td>\n<\/tr>\n
ApoB<\/td>\n100\u00b15<\/td>\n101\u00b16<\/td>\n100\u00b15<\/td>\n100\u00b16<\/td>\n<\/tr>\n
ApoB-48<\/td>\n0.53\u00b10.04<\/td>\n0.82\u00b10.08\u2020<\/sup><\/td>\n0.99\u00b10.14\u2020<\/sup><\/td>\n0.92\u00b10.14\u2020<\/sup><\/td>\n<\/tr>\n
RLP-TG\/TG<\/td>\n0.13\u00b10.04<\/td>\n0.41 \u00b10.12<\/td>\n0.46\u00b10.14<\/td>\n0.36\u00b10.13<\/td>\n<\/tr>\n
RLP-TG\/RLP-C<\/td>\n2.8\u00b10.4<\/td>\n8.5\u00b10.9\u2020<\/sup><\/td>\n12.3\u00b11.5\u2020<\/sup><\/td>\n7.8\u00b10.9\u2020<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u3053\u306e\u30c7\u30fc\u30bf\u3067\u308f\u304b\u308b\u3053\u3068\u306f\u3001\u307e\u305aApoB\u304c\u8102\u80aa\u8ca0\u8377\u306e\u5f8c\u3067\u5909\u52d5\u3057\u3066\u3044\u306a\u3044\u3053\u3068\u3067\u3059\u3002ApoB\u306e\u591a\u304f\u306fApoB100\u3068\u3044\u3046\u3001VLDL\u3084LDL\u306e\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002VLDL\u306f\u809d\u81d3\u3067\u4f5c\u3089\u308c\u307e\u3059\u3002ApoB\u304c\u5909\u5316\u3057\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u809d\u81d3\u304c\u5206\u6ccc\u3059\u308bVLDL\u306f\u307b\u3068\u3093\u3069\u8102\u80aa\u8ca0\u8377\u3067\u5909\u5316\u3057\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002ApoB48\u3068\u3044\u3046\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u8102\u80aa\u8ca0\u8377\u5f8c\u306b4\u6642\u9593\u5f8c\u3092\u30d4\u30fc\u30af\u3068\u3057\u3066\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e2d\u6027\u8102\u80aa\u3092\u898b\u3066\u307f\u308b\u3068\u3001\u3053\u308c\u30824\u6642\u9593\u5f8c\u3092\u30d4\u30fc\u30af\u306b\u6fc0\u5897\u3057\u3066\u3044\u307e\u3059\u3057\u3001\u30ec\u30e0\u30ca\u30f3\u30c8\u306e\u4e2d\u6027\u8102\u80aa\u3082\u3053\u308c\u307e\u305f4\u6642\u9593\u5f8c\u3092\u30d4\u30fc\u30af\u306b\u6fc0\u5897\u3057\u3066\u3044\u307e\u3059\u3002\u4e2d\u6027\u8102\u80aa\u306e\u5897\u52a0\u304c109\u3067\u3042\u308a\u3001\u30ec\u30e0\u30ca\u30f3\u30c8\u306e\u4e2d\u6027\u8102\u80aa\u306e\u5897\u52a0\u304c87\u3067\u3059\u3002\u3064\u307e\u308a\u3001\u5897\u52a0\u3057\u305f\u4e2d\u6027\u8102\u80aa\u306e\u7d0480\uff05\u306f\u30ec\u30e0\u30ca\u30f3\u30c8\u306e\u3082\u306e\u3067\u3059\u3002<\/p>\n

\u305d\u3057\u3066\u3001VLDL\u306f\u5897\u52a0\u305b\u305a\u3001\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306fApoB48\u306e\u5897\u52a0\u304b\u3089\u8003\u3048\u3066\u3001\u5897\u52a0\u3057\u3066\u3044\u308b\u306e\u306f\u660e\u3089\u304b\u306a\u306e\u3067\u3001\u3053\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u306e\u4e2d\u6027\u8102\u80aa\u306e\u591a\u304f\u306f\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

ApoB48\u306f6\u6642\u9593\u5f8c\u3067\u3082\u305d\u308c\u307b\u3069\u6e1b\u5c11\u3057\u3066\u3044\u306a\u3044\u306e\u3067\u3001\u30b5\u30a4\u30ba\u306f\u5c0f\u3055\u304f\u306a\u3063\u305f\u3068\u3057\u3066\u3082\u3001\u307e\u3060\u307e\u3060\u3057\u3070\u3089\u304f\u6b8b\u5b58\u3057\u305f\u307e\u307e\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

6\u6642\u9593\u5f8c\u307e\u30674\u6642\u9593\u5f8c\u306bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u3084\u3084\u4f4e\u4e0b\u3057\u305f\u4ee5\u5916\u3001HDL\u3082LDL\u3082\u307b\u3068\u3093\u3069\u5909\u52d5\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n

\u3055\u3089\u306b\u307b\u304b\u306e\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u793a\u3057\u307e\u3059\u3002\u5065\u5eb7\u306a\u4eba\u306e\u7a7a\u8179\u6642\u3068\u671d\u98df\u5f8c4\u6642\u9593\u5f8c\u3001\u305d\u3057\u3066\u671d\u98df\u304b\u30894\u6642\u9593\u5f8c\u306b\u306f\u663c\u98df\u3092\u6442\u308a\u3001\u305d\u306e4\u6642\u9593\u5f8c\uff08\u671d\u98df\u304b\u3089\u6570\u3048\u308b\u30688\u6642\u9593\u5f8c\uff09\u306e\u30c7\u30fc\u30bf\u3067\u3059\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5909\u6570\uff08mg\/dL\uff09<\/th>\n\u7a7a\u8179\u6642<\/th>\n\u98df\u5f8c<\/p>\n
\n<\/th>\n<\/tr>\n
<\/th>\n<\/th>\n4\u6642\u9593<\/th>\n\u5909\u5316\u7387\uff08\uff05\uff09<\/th>\n8\u6642\u9593<\/th>\n\u5909\u5316\u7387\uff08\uff05\uff09<\/th>\n<\/tr>\n<\/thead>\n
TC<\/td>\n184.9\uff0821.4\uff09<\/td>\n181.7\uff0822.6\uff09<\/td>\n-1.8\uff083.3\uff09*<\/sup><\/td>\n182.2\uff0821.9\uff09<\/td>\n-1.4\uff085.3\uff09*<\/sup><\/td>\n<\/tr>\n
TG<\/td>\n90 [71-117]<\/td>\n116 [97-159]<\/td>\n+50 [21-76]\u00a0\u2020<\/sup><\/td>\n132 [90-230]<\/td>\n+65.8 [30-86]\u00a0\u2020<\/sup><\/td>\n<\/tr>\n
HDL-C<\/td>\n52.4\uff088.6\uff09<\/td>\n49.2\uff089.3\uff09<\/td>\n-6.3\uff086.6\uff09*<\/sup><\/td>\n47.7\uff0810.5\uff09<\/td>\n-9.6\uff088.8\uff09\u2020<\/sup><\/td>\n<\/tr>\n
\u975eHDL-C<\/td>\n132.5\uff0823.9\uff09<\/td>\n132.5\uff0825.9\uff09<\/td>\n-0.2\uff084.8\uff09*<\/sup><\/td>\n134.5\uff0827.6\uff09<\/td>\n+1.3\uff087.5\uff09*<\/sup><\/td>\n<\/tr>\n
LDL-C<\/td>\n111.8\uff0820.8\uff09<\/td>\n105.6\uff0821.2\uff09<\/td>\n-5.6\uff084.2\uff09\u2020<\/sup><\/td>\n105.2\uff0820.5\uff09<\/td>\n-6.0\uff085.5\uff09\u2020<\/sup><\/td>\n<\/tr>\n
RemL-C<\/td>\n5.4 [3-7]<\/td>\n5.9 [4-8]<\/td>\n+32.6 [6-48]\u00a0\u2020<\/sup><\/td>\n5.7 [4-11]<\/td>\n+ 22.6 [6-62]\u00a0*<\/sup><\/td>\n<\/tr>\n
\u7dcfApoB<\/td>\n81.2\uff0814.1\uff09<\/td>\n79.8\uff0814.0\uff09<\/td>\n-1.6\uff086.4\uff09*<\/sup><\/td>\n79.2\uff0815.6\uff09<\/td>\n-2.7\uff086.7\uff09*<\/sup><\/td>\n<\/tr>\n
Apo B-48<\/td>\n0.51 [0.4-0.8]<\/td>\n1.24 [0.9-1.4]<\/td>\n+121.3 [90-163]\u00a0\u2021<\/sup><\/td>\n1.42 [0.9-2.0]<\/td>\n+147.2 [94-231]\u00a0\u2021<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5148\u307b\u3069\u306e\u7814\u7a76\u3068\u540c\u3058\u3088\u3046\u306b\u3001ApoB\u306f\u5909\u5316\u3057\u3066\u3044\u306a\u3044\u3070\u304b\u308a\u304b\u3084\u3084\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e00\u65b9\u3067ApoB48\u306f\u671d\u98df\u5f8c4\u6642\u9593\u3067\u5897\u52a0\u3057\u3001\u663c\u98df\u5f8c4\u6642\u9593\u3067\u3055\u3089\u306b\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u4e2d\u6027\u8102\u80aa\u30824\u6642\u9593\u5f8c\u5897\u52a0\u3057\u3001\u663c\u98df\u5f8c4\u6642\u9593\u5f8c\u3067\u3082\u3055\u3089\u306b\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u3053\u3053\u3067\u3082\u4e2d\u6027\u8102\u80aa\u5024\u306e\u5897\u52a0\u306f\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306b\u3088\u308b\u3068\u3053\u308d\u304c\u975e\u5e38\u306b\u5927\u304d\u3044\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u3002LDL\u3084HDL\u306f\u3001\u3080\u3057\u308d\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u5148\u307b\u3069\u3068\u540c\u3058\u3067\u3059\u3002<\/p>\n

\u3053\u306e\u7814\u7a76\u3067\u306f\u80a5\u6e80\u306e\u4eba\u306e\u30c7\u30fc\u30bf\u3082\u53d6\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u80a5\u6e80\u306e\u4eba\u3067\u306f\u3084\u306f\u308a\u7a7a\u8179\u6642\u306eApoB48\u304c0.82\u3068\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3084\u306f\u308a\u3001\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u306e\u30ec\u30e0\u30ca\u30f3\u30c8\u304c\u6d88\u3048\u5207\u3063\u3066\u3044\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

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 <\/p>\n

\u300cFasting and postprandial apolipoprotein B-48 levels in healthy, obese, and hyperlipidemic subjects\u300d<\/span><\/p>\n

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\u300cRemnant Lipoproteins: A Subfraction of Plasma Triglyceride-Rich Lipoproteins Associated with Postprandial Hyperlipidemia\u300d<\/span><\/p>\n

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