{"id":5807,"date":"2018-10-17T08:43:17","date_gmt":"2018-10-16T23:43:17","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=5807"},"modified":"2020-01-10T08:39:44","modified_gmt":"2020-01-09T23:39:44","slug":"post-5807","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=5807","title":{"rendered":"LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u306e\u6709\u76ca\u6027\u306e\u8a3c\u62e0\u306f\u306a\u3044\uff01"},"content":{"rendered":"

\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u3044\u307e\u3060\u306b\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u4e88\u9632\u3067\u304d\u308b\u3068\u601d\u3063\u3066\u3044\u308b\u4eba\u304c\u3044\u307e\u3059\u3002\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u60aa\u7389\u8aac\u304c\u69d8\u3005\u306a\u6cbb\u7642\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u30d9\u30fc\u30b9\u306b\u306a\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u304c\u3001\u3061\u3083\u3093\u3068\u3057\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

2004\u5e74\u306e\u81e8\u5e8a\u8a66\u9a13\u898f\u5236\u306e\u767a\u8868\u5f8c\u306b\u5831\u544a\u3055\u308c\u305f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u3059\u3079\u3066\u898b\u3066\u307f\u308b\u3068\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u306e\u6709\u76ca\u6027\u306e\u8a3c\u62e0\u306f\u8a8d\u3081\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n

29\u306e\u7814\u7a76\u306e\u3046\u30612\u3064\u3060\u3051\u304c\u6b7b\u4ea1\u7387\u3078\u306e\u6709\u76ca\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u305d\u3057\u3066\u3001\u307b\u307c3\u5206\u306e2\u306f\u5fc3\u81d3\u8840\u7ba1\u75be\u60a3\u3078\u306e\u6709\u76ca\u6027\u3092\u8a8d\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u4e0b\u306e\u8868\u3092\u898b\u3066\u304f\u3060\u3055\u3044\u3002\uff08\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
2004\u5e74\u306e\u81e8\u5e8a\u8a66\u9a13\u898f\u5236\u306e\u767a\u8868\u5f8c\u306b\u5831\u544a\u3055\u308c\u305f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\u306e\u7121\u4f5c\u70ba\u5316\u5bfe\u7167<\/span>\u8a66\u9a13<\/caption>\n
\u5e74<\/th>\n\u4ecb\u5165<\/th>\n\u7814\u7a76\u671f\u9593<\/th>\n\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b<\/th>\n\u6b7b\u4ea1\u7387\u3078\u306e\u6709\u76ca\u6027<\/th>\n\u5fc3\u8840\u7ba1\u75be\u60a3\u3078\u306e\u6709\u76ca\u6027<\/th>\n<\/tr>\n
2005\u5e74<\/td>\n\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f320mg \/\u65e5<\/td>\n4.3 \u5e74<\/td>\n39\uff05-43\uff05LDL<\/td>\n\u30fc<\/td>\n\u306a\u3057<\/span>\uff08P = 0.08\uff09<\/td>\n<\/tr>\n
2005\u5e74<\/td>\n\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f310mg \/ \u65e5\u307e\u305f\u306f80mg \/ \u65e5<\/td>\n4.9\u5e74<\/td>\n24\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR1.01; 95\uff05CI\u30010.85-1.19\uff09<\/td>\n\u3042\u308a\uff08HR 0.78; 95\uff05CI\u30010.69-0.89\uff09<\/td>\n<\/tr>\n
2005\u5e74<\/td>\n\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f380mg \/ \u65e5\u307e\u305f\u306f\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f320mg \/ d<\/td>\n4.8\u5e74<\/td>\n20\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.98; 95\uff05CI\u30010.85-1.13\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.89; 95\uff05CI\u30010.78-1.01\uff09<\/td>\n<\/tr>\n
2005\u5e74<\/td>\n\u30d5\u30a7\u30ce\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8200mg \/\u65e5<\/td>\n6\u5e74<\/td>\n12\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR1.1; 95\uff05CI\u30010.95-1.29\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.89; 95\uff05CI\u30010.75-1.05\uff09<\/td>\n<\/tr>\n
2005\u5e74<\/td>\n\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f320mg \/\u65e5<\/td>\n4\u5e74<\/td>\n42\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08RR 0.93; 95\uff05CI\u30010.79-1.08\uff09<\/td>\n\u306a\u3057<\/span>\uff08RR 0.92; 95\uff05CI\u30010.77-1.10\uff09<\/td>\n<\/tr>\n
2006\u5e74<\/td>\n\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f310mg \/\u65e5<\/td>\n4\u5e74<\/td>\n29\uff05LDL<\/td>\n\u306a\u3057<\/span><\/td>\n\u306a\u3057<\/span>\uff08HR 0.9; 95\uff05CI\u30010.73-1.12\uff09<\/td>\n<\/tr>\n
2006\u5e74<\/td>\n\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f380mg \/\u65e5<\/td>\n4.9\u5e74<\/td>\n43\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 1.0; 95\uff05CI\u30010.82-1.21\uff09<\/td>\n\u3042\u308a\uff08HR 0.84; 95\uff05CI\u30010.71-0.99\uff09<\/td>\n<\/tr>\n
2006\u5e74<\/td>\n\u4f4e\u8102\u80aa\u98df<\/td>\n8.1\u5e74<\/td>\n7\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 1.01,95\uff05CI\u30010.81-1.27\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.97; 95\uff05CI\u30010.9-1.06\uff09<\/td>\n<\/tr>\n
2006\u5e74<\/td>\n\u30d7\u30e9\u30d0\u30b9\u30bf\u30c1\u30f310-20mg \/\u65e5<\/td>\n5.3\u5e74<\/td>\n15\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.72; 95\uff05CI\u30010.51-1.01\uff09<\/td>\n\u3042\u308a\uff08HR 0.67; 95\uff05CI\u30010.49-0.91\uff09<\/td>\n<\/tr>\n
2007\u5e74<\/td>\n\u30c8\u30eb\u30bb\u30c8\u30e9\u30d4\u30d6<\/td>\n2.2 \u5e74<\/td>\n25\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 1.58; 95\uff05CI\u30011.14-2.19\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 1.25; 95\uff05CI\u30011.09-1.44\uff09<\/td>\n<\/tr>\n
2007\u5e74<\/td>\n\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f310mg \/\u65e5<\/td>\n33\u30f6\u6708<\/td>\n45\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.95; 95\uff05CI\u30010.86-1.05\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.92; 95\uff05CI\u30010.83-1.02\uff09<\/td>\n<\/tr>\n
2008\u5e74<\/td>\n\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f340mg +\u30a8\u30bc\u30c1\u30df\u30d610mg \/ \u65e5<\/td>\n4.4\u5e74<\/td>\n50\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR1.04; 95\uff05CI\u30010.79-1.36\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.96; 95\uff05CI\u30010.83-1.12\uff09<\/td>\n<\/tr>\n
2008\u5e74<\/td>\n\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f310mg \/\u65e5<\/td>\n3.9\u5e74<\/td>\n27\uff05\u301c32\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08RR 1.00; 95\uff05CI\u30010.90-1.22\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR1.01; 95\uff05CI\u30010.91-1.11\uff09<\/td>\n<\/tr>\n
2008\u5e74<\/td>\n\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f320mg \/\u65e5<\/td>\n1.9\u5e74<\/td>\n49\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.81; 95\uff05CI\u30010.63-1.04\uff09<\/td>\n\u3042\u308a\uff08HR 0.55; 95\uff05CI\u30010.43-0.69\uff09<\/td>\n<\/tr>\n
2009\u5e74<\/td>\n\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f310mg \/\u65e5<\/td>\n3.8 \u5e74<\/td>\n43\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.96; 95\uff05CI\u30010.86-1.07\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.96; 95\uff05CI\u30010.84-1.11\uff09<\/td>\n<\/tr>\n
2010\u5e74<\/td>\n\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f380\u307e\u305f\u306f20mg \/ \u65e5<\/td>\n6.7\u5e74<\/td>\n0.35mmol \/ L LDL<\/td>\n\u306a\u3057<\/span>\uff08RR 0.99; 95\uff05CI\u30010.91-1.09\uff09<\/td>\n\u306a\u3057<\/span>\uff08RR 0.94; 95\uff05CI\u30010.88-1.01\uff09<\/td>\n<\/tr>\n
2011\u5e74<\/td>\n\u30ca\u30a4\u30a2\u30b7\u30f3ER 1.5-2.0g \/ \u65e5<\/td>\n3\u5e74<\/td>\n16\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR1.16; 95\uff05CI\u30010.87-1.56\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR1.02; 95\uff05CI\u30010.87-1.21\uff09<\/td>\n<\/tr>\n
2011\u5e74<\/td>\n\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f320mg \/ \u65e5 +\u30a8\u30bc\u30c1\u30df\u30d610mg \/ \u65e5<\/td>\n4.9\u5e74<\/td>\n31\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08RR 1.01; 95\uff05CI\u30010.75-1.35\uff09CHD\u6b7b\u4ea1<\/td>\n\u3042\u308a\uff08RR 0.83; 95\uff05CI\u30010.74-0.94\uff09<\/td>\n<\/tr>\n
2013\u5e74<\/td>\nPUFA\u307e\u305f\u306fSFA\u98df<\/td>\n39\u30f6\u6708<\/td>\n7.8\uff05\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u306a\u3057<\/span>\uff08HR 1.62; 95\uff05CI\u30011.00-2.64\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 1.70; 95\uff05CI\u30011.03-2.80\uff09<\/td>\n<\/tr>\n
2014<\/td>\n\u30ca\u30a4\u30a2\u30b7\u30f3ER 2g \/ \u65e5 +\u30e9\u30ed\u30d4\u30d7\u30e9\u30f3\u30c840mg \/ \u65e5<\/td>\n3.9\u5e74<\/td>\n16\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08RtR1.09; 95\uff05CI\u30010.99-1.21\uff09<\/td>\n\u306a\u3057<\/span>\uff08RtR 0.96; 95\uff05CI\u30010.90-1.03\uff09<\/td>\n<\/tr>\n
2015\u5e74<\/td>\n\u30a8\u30bc\u30c1\u30df\u30d610mg \/\u65e5<\/td>\n7\u5e74<\/td>\n24\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.99; 95\uff05CI\u30010.91-1.07\uff09<\/td>\n\u3042\u308a\uff08HR 0.94; 95\uff05CI\u30010.89-0.99\uff09<\/td>\n<\/tr>\n
2016\u5e74<\/td>\nPUFA\u307e\u305f\u306fSFA\u98df<\/td>\n41-56\u304b\u6708<\/td>\n13\uff05\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/td>\n\u306a\u3057<\/span>\uff08HR1.2; 95\uff05CI\u30011.14-1.32\uff09<\/td>\n\u30fc<\/td>\n<\/tr>\n
2016\u5e74<\/td>\n\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f310mg \/\u65e5<\/td>\n5.6\u5e74<\/td>\n26\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.93; 95\uff05CI\u30010.80-1.08\uff09<\/td>\n\u3042\u308a\uff08HR 0.76; 95\uff05CI\u30010.64-0.91\uff09<\/td>\n<\/tr>\n
2017\u5e74<\/td>\n\u30a8\u30d0\u30bb\u30d7\u30c1\u30d6130mg \/\u65e5<\/td>\n26\u30f6\u6708<\/td>\n37\uff05LDL<\/td>\n\u3042\u308a\uff08HR 0.84; 95\uff05CI\u30010.70-1.00\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR1.01; 95\uff05CI\u30010.91-1.11\uff09<\/td>\n<\/tr>\n
2017\u5e74<\/td>\n\u30a8\u30bc\u30c1\u30df\u30d610mg \/\u65e5<\/td>\n3.9\u5e74<\/td>\n15\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 0.70; 95\uff05CI\u30010.47-1.04\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.89; 95\uff05CI\u30010.76-1.04\uff09<\/td>\n<\/tr>\n
2017\u5e74<\/td>\n\u30a8\u30dc\u30ed\u30af\u30de\u30d6140mg 2\u9031\u9593\u6bce\u307e\u305f\u306f420mg \/\u65e5<\/td>\n2.2
\n\u5e74<\/td>\n		59\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR1.04; 95\uff05CI\u30010.91-1.19\uff09<\/td>\n\u3042\u308a\uff08HR 0.85; 95\uff05CI\u30010.79-0.92\uff09<\/td>\n<\/tr>\n
2017\u5e74<\/td>\n\u30a2\u30ca\u30bb\u30e9\u30d4\u30d6100mg \/\u65e5<\/td>\n4.1 \u5e74<\/td>\n41\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08P = .46\uff09<\/td>\n\u3042\u308a\uff08RR 0.91; 95\uff05CI\u30010.85-0.97\uff09<\/td>\n<\/tr>\n
2018\u5e74<\/td>\n\u5f37\u5316\u3068\u6a19\u6e96\u7528\u91cf\u30b9\u30bf\u30c1\u30f3<\/td>\n60\u30f6\u6708<\/td>\n26\uff05LDL<\/td>\n\u306a\u3057<\/span>\uff08HR 1.21; 95\uff05CI\u30010.77-1.91\uff09<\/td>\n\u306a\u3057<\/span>\uff08HR 0.84; 95\uff05CI\u30010.67-1.07\uff09<\/td>\n<\/tr>\n
2018\u5e74<\/td>\n\u30a2\u30ea\u30ed\u30af\u30de\u30d675-150 mg \uff12\u9031\u9593\u6bce<\/td>\n2.8 \u5e74<\/td>\n55\uff05LDL<\/td>\n\u3042\u308a\uff08HR 0.85,95\uff05CI\u30010.73-0.98\uff09<\/td>\n\u3042\u308a\uff08HR 0.85; 95\uff05CI\u30010.78-0.93\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u52d5\u8108\u786c\u5316\u75c7\u306e\u30d7\u30e9\u30fc\u30af\u306e\u6210\u5206\u3067\u3042\u308b\u3053\u3068\u306f\u78ba\u304b\u3067\u3059\u3002\u3057\u304b\u3057\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u539f\u56e0\u3060\u3068\u3044\u3046\u8a3c\u62e0\u306f\u3042\u308a\u307e\u305b\u3093\u3002LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u539f\u56e0\u3067\u3042\u308b\u3068\u3044\u3046\u4e3b\u5f35\u306b\u3088\u308a\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u4e88\u9632\u306b\u306a\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u6b63\u5f53\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u5f37\u56fa\u306a\u8a3c\u62e0\u3082\u306a\u304f\u30b9\u30bf\u30c1\u30f3\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u4e0a\u306e\u3088\u3046\u306b\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u77db\u76fe\u3057\u305f\u7d50\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3046\u3067\u3042\u308b\u306a\u3089\u3070\u3001\u305d\u308d\u305d\u308d\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u60aa\u7389\u8aac\u3092\u3084\u3081\u308b\u3079\u304d\u3067\u3059\u3002\u30b9\u30bf\u30c1\u30f3\u306f\u69d8\u3005\u306a\u526f\u4f5c\u7528\u304c\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u77db\u76fe\u3057\u305f\u8a3c\u62e0\u3092\u7121\u8996\u3057\u3066\u3001\u3080\u3084\u307f\u306b\u4e0d\u5fc5\u8981\u306a\u4eba\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4ee5\u524d\u306e\u8a18\u4e8b\u300c\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u304b\u3089\u8003\u3048\u308b\u3000\u9ad8LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u539f\u56e0\u3067\u306f\u306a\u3044\u3000\u305d\u306e1<\/a>\u300d\u300c\u305d\u306e2<\/a>\u300d\u306a\u3069\u306b\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306e\u4eba\u3067\u3055\u3048\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u6069\u6075\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u300cLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u672c\u5f53\u306b\u52d5\u8108\u306e\u8840\u7ba1\u5185\u8154\u304b\u3089\u8840\u7ba1\u5185\u76ae\u3092\u901a\u3063\u3066\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u3092\u8d77\u3053\u3059\u306e\u304b\uff1f\u3000\u305d\u306e9\u3000\u5225\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u904b\u3073\u5c4b<\/a>\u300d\u3067\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u904b\u3076\u306e\u3082LDL\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3057\u3066\u3001\u51dd\u56fa\u7cfb\u306e\u554f\u984c\u304c\u5927\u304d\u304f\u304b\u304b\u308f\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3001\u5358\u7d14\u306aLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\u7642\u6cd5\u3067\u89e3\u6c7a\u3067\u304d\u308b\u3088\u3046\u306a\u554f\u984c\u3067\u306f\u306a\u3044\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n

\u300c\u975e\u5e38\u306b\u4f4e\u3044LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u6b7b\u4ea1\u7387\u3084\u5fc3\u75be\u60a3\u30ea\u30b9\u30af\u4f4e\u4e0b\u306b\u95a2\u9023\u3057\u3066\u3044\u306a\u3044<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u95a2\u9023\u6027\u306f\u975e\u5e38\u306b\u4f4e\u3044\u53ef\u80fd\u6027\u306e\u65b9\u304c\u9ad8\u3044\u306e\u3067\u3059\u3002<\/p>\n

LDL\u306e\u4e2d\u3067\u5371\u967a\u306aLDL\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308bsdLDL\u306fHDL\u3084\u4e2d\u6027\u8102\u80aa\u5024\u3068\u306e\u304b\u304b\u308f\u308a\u306e\u65b9\u304c\u5927\u304d\u304f\u3001\u3055\u3089\u306bHDL\u3084\u4e2d\u6027\u8102\u80aa\u5024\u306f\u7cd6\u8cea\u6442\u53d6\u3068\u306e\u95a2\u9023\u3082\u5927\u304d\u3044\u306e\u3067\u3059\u3002\uff08\u300c\u7cd6\u8cea\u5236\u9650\u3068LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4e0a\u6607<\/a>\u300d\u306a\u3069\u53c2\u7167\uff09<\/p>\n

\u526f\u4f5c\u7528\u306b\u82e6\u3057\u3080\u30b9\u30bf\u30c1\u30f3\u3088\u308a\u3082\u7cd6\u8cea\u5236\u9650\u306e\u65b9\u304c\u30ea\u30b9\u30af\u3082\u306a\u304f\u3001\u52b9\u679c\u3082\u5927\u304d\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u300cA Reappraisal of the Lipid Hypothesis\u300d<\/span><\/p>\n

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