{"id":6020,"date":"2018-11-05T08:51:13","date_gmt":"2018-11-04T23:51:13","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=6020"},"modified":"2018-11-05T08:51:13","modified_gmt":"2018-11-04T23:51:13","slug":"post-6020","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=6020","title":{"rendered":"\u7dd1\u5185\u969c\u306f\u7cd6\u8cea\u5236\u9650\u3092\u3059\u3079\u304d\u3067\u3042\u308b\u3000\u305d\u306e2\u30004\u578b\u7cd6\u5c3f\u75c5\uff1f\u773c\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\uff1f"},"content":{"rendered":"

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\u7db2\u819c\u795e\u7d4c\u7bc0\u7d30\u80de\uff08RGC\uff09\u306e\u751f\u5b58\u306b\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306b\u3088\u308a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u4e0d\u5168\u304c\u8d77\u304d\u308b\u3068\u3001RGC\u306f\u6b7b\u3093\u3067\u3057\u307e\u3046\u3088\u3046\u3067\u3059\u3002<\/p>\n

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\u3055\u3089\u306b\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u7dd1\u5185\u969c\u3060\u3051\u3067\u306a\u304f\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7\u60a3\u8005\u306e\u785d\u5b50\u4f53\u6db2\u4e2d\u306b\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6e1b\u5c11\u3068\u30bf\u30a6\u306e\u5897\u52a0\u3068\u3044\u3046\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u810a\u9ac4\u6db2\u4e2d\u306e\u5909\u5316\u3068\u985e\u4f3c\u306e\u5909\u5316\u304c\u8d77\u304d\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u3053\u3068\u306b\u3088\u308a\u3001\u7dd1\u5185\u969c\u3084\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7\u60a3\u8005\u306e\u7db2\u819c\u4e2d\u306b\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u304c\u84c4\u7a4d\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u8868\u306f\u3053\u306e\u8ad6\u6587<\/a>\u3088\u308a\u6539\u5909\uff09<\/p>\n\n\n\n\n\n
\u785d\u5b50\u4f53\u4e2d\u306e\u6fc3\u5ea6<\/td>\n\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb<\/td>\n\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7<\/td>\n\u7dd1\u5185\u969c<\/td>\n<\/tr>\n
\u30a2\u30df\u30ed\u30a4\u30c9\u03b2-42 (pg\/ml)<\/td>\n33.9<\/td>\n1.8<\/td>\n2.8<\/td>\n<\/tr>\n
\u30bf\u30a6\u00a0(pg\/ml)<\/td>\n3.3<\/td>\n153.7<\/td>\n113.6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u3053\u306e\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u3082\u3057\u304b\u3059\u308b\u3068\u7dd1\u5185\u969c\u3082\u7cd6\u5c3f\u75c5\u7db2\u819c\u75c7\u3082\u75c5\u7406\u5b66\u7684\u306b\u306f\u540c\u3058\u3082\u306e\u3067\u3042\u308a\u3001\u75c7\u72b6\u3068\u3057\u3066\u306e\u8868\u308c\u65b9\u306e\u9055\u3044\u3060\u3051\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u3001\u7dd1\u5185\u969c\u3068\u7cd6\u5c3f\u75c5\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u95a2\u9023\u3092\u793a\u5506\u3059\u308b\u3082\u306e\u3060\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n

\u795e\u7d4c\u7d30\u80de\u306f\u975e\u5e38\u306b\u9ad8\u3044\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u6301\u3061\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6d3b\u6027\u3082\u975e\u5e38\u306b\u9ad8\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u4e0d\u5168\u306b\u3088\u308a\u6d3b\u6027\u9178\u7d20\u7a2e\uff08ROS\uff09\u304c\u767a\u751f\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u4e0d\u5168\u3082RGC\u3092\u50b7\u5bb3\u3057\u3001\u7dd1\u5185\u969c\u3092\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u4e0d\u5168\u3092\u8d77\u3053\u3059\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306f\u7dd1\u5185\u969c\u306e\u5371\u967a\u56e0\u5b50\u306e\u773c\u5727\u3082\u4e0a\u6607\u3055\u305b\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3055\u3089\u306b\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u795e\u7d4c\u7d30\u80de\u306e\u751f\u5b58\u306b\u91cd\u8981\u306aRGC\u3092\u542b\u3093\u3060\u7db2\u819c\u306e3\u3064\u306e\u5c64\u3067\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u8f38\u9001\u4f53GLUT4\u306e\u767a\u73fe\u3092\u8a98\u5c0e\u3057\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u6b20\u4e4f\u307e\u305f\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306f\u3001RGC\u306e\u50b7\u5bb3\u3084\u6b7b\u3092\u5f15\u304d\u8d77\u3053\u3059\u306e\u3067\u3059\u3002<\/p>\n

\u305d\u3057\u3066\u3001\u8133\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u4e00\u3064\u3067\u3042\u308b\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306e\u904e\u5270\u306a\u6d3b\u6027\u306f\u795e\u7d4c\u7d30\u80de\u306b\u6b7b\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u3053\u306e\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u3082\u7dd1\u5185\u969c\u306b\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306e\u6bd2\u6027\u304b\u3089\u795e\u7d4c\u3092\u4fdd\u8b77\u3059\u308b\u5f79\u5272\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7dd1\u5185\u969c\u3082\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u540c\u3058\u3088\u3046\u306b\u591a\u56e0\u5b50\u6027\u306e\u75be\u60a3\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u773c\u5727\u3060\u3051\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u3066\u3082\u9032\u884c\u3059\u308b\u306e\u306f\u305d\u306e\u305f\u3081\u3067\u3059\u3002\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3084\u4ed6\u306e\u75be\u60a3\u3068\u540c\u3058\u3088\u3046\u306b\u708e\u75c7\u3082\u91cd\u8981\u306a\u56e0\u5b50\u306e\u4e00\u3064\u3067\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u708e\u75c7\u3092\u6291\u3048\u308b\u4f5c\u7528\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u5fae\u5c0f\u5faa\u74b0\u8840\u6d41\u3092\u5897\u52a0\u3055\u305b\u3001\u7d44\u7e54\u306e\u865a\u8840\u3092\u9632\u3050\u3068\u3044\u3046\u4f5c\u7528\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u3088\u3046\u306b\u5341\u5206\u306a\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u5206\u6ccc\u3055\u308c\u306a\u3044\u304b\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3067\u5341\u5206\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u4f5c\u7528\u304c\u50cd\u304b\u306a\u304f\u306a\u3063\u305f\u4e2d\u67a2\u795e\u7d4c\u3067\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3084\u7dd1\u5185\u969c\u304c\u8d77\u3053\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002\u9006\u306b\u8003\u3048\u308c\u3070\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u9069\u5207\u306a\u91cf\u304c\u4fdd\u305f\u308c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u3061\u3083\u3093\u3068\u50cd\u304f\u3053\u3068\u304c\u305d\u308c\u3089\u306e\u75be\u60a3\u306e\u4e88\u9632\u306b\u3082\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u6700\u521d\u306e\u65b9\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u5168\u8eab\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5897\u52a0\u306b\u76f8\u95a2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u9ac4\u6db2\u306e\u7cd6\u306f\u3059\u3079\u3066\u8840\u7cd6\u306b\u7531\u6765\u3057\u3066\u304a\u308a\u3001\u305d\u306e\u6fc3\u5ea6\u306f\u8840\u7cd6\u5024\u306b\u5927\u304d\u304f\u4f9d\u5b58\u3057\u3001\u8840\u7cd6\u5024\u306e60\uff5e70\uff05\u7a0b\u5ea6\u306e\u5024\u3092\u793a\u3057\u307e\u3059\u3002\u3067\u3059\u304b\u3089\u3001\u5168\u8eab\u3067\u9ad8\u8840\u7cd6\u3068\u306a\u308c\u3070\u5f53\u7136\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3067\u3082\u7cd6\u6fc3\u5ea6\u306f\u9ad8\u304f\u306a\u308a\u3001\u305d\u306e\u5206\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u3082\u591a\u304f\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u8133\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3082\u6050\u3089\u304f\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u7cd6\u304c\u9ad8\u6fc3\u5ea6\u306b\u983b\u7e41\u306b\u306a\u308a\u3001\u6700\u521d\u306f\u305f\u304f\u3055\u3093\u5206\u6ccc\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u3046\u3061\u52b9\u304d\u76ee\u304c\u60aa\u304f\u306a\u308a\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u304f\u306a\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n

\u8133\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3042\u308b\u3044\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4f4e\u4e0b\u3001\u5168\u8eab\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3042\u308b\u3044\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4f4e\u4e0b\u304c\u540c\u3058\u3088\u3046\u306b\u30d1\u30e9\u30ec\u30eb\u306b\u8d77\u304d\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u305d\u308c\u305e\u308c\u306e\u7a0b\u5ea6\u306b\u3088\u308a\u3001\u795e\u7d4c\u5909\u6027\u75be\u60a3\u3067\u3042\u308b\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3084\u7dd1\u5185\u969c\u304c\u8d77\u304d\u308b\u304b\u3001\u5168\u8eab\u306e\u7cd6\u5c3f\u75c5\u304c\u8d77\u304d\u308b\u304b\u3001\u3069\u308c\u304b\u304c\u8d77\u304d\u308b\u304b\u3001\u3069\u308c\u3082\u5168\u90e8\u8d77\u304d\u308b\u304b\u69d8\u3005\u306a\u7d44\u307f\u5408\u308f\u305b\u304c\u8d77\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u306e\u3067\u3059\u3002<\/p>\n

\u3082\u3057\u304b\u3057\u305f\u3089\u7dd1\u5185\u969c\u306f\u5c06\u6765\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3092\u4e88\u6e2c\u3059\u308b\u3082\u306e\u3067\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3057\u3001\u773c\u5727\u306e\u4e0a\u6607\u306f\u8133\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u30a2\u30e9\u30fc\u30e0\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u305d\u3046\u3067\u3042\u308c\u3070\u773c\u79d1\u306b\u884c\u3063\u3066\u76ee\u85ac\u3092\u3082\u3089\u3063\u3066\u5b89\u5fc3\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u7cd6\u8cea\u5236\u9650\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001\u5168\u3066\u306e\u6839\u672c\u539f\u56e0\u306f\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306b\u3088\u308b\u9ad8\u8840\u7cd6\u3067\u3059\u3002\u305d\u308c\u306b\u3088\u308a\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u306a\u3055\u308c\u308b\u308f\u3051\u3067\u3059\u304b\u3089\u3002<\/p>\n

\u7cd6\u8cea\u5236\u9650\u306f\u98df\u5f8c\u9ad8\u8840\u7cd6\u304a\u3088\u3073\u904e\u5270\u306a\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3059\u308b\u306e\u3067\u3001\u8133\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u8d77\u304d\u308b\u30ea\u30b9\u30af\u306f\u975e\u5e38\u306b\u4f4e\u304f\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\u7cd6\u5c3f\u75c5\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3001\u305d\u3057\u3066\u7dd1\u5185\u969c\u3092\u4e88\u9632\u3059\u308b\u306b\u306f\u7cd6\u8cea\u5236\u9650\u3067\u3059\u3002<\/p>\n

 <\/p>\n

\u300cDiabetes Type 4: A Paradigm Shift in the Understanding of Glaucoma, the Brain Specific Diabetes and the Candidature of Insulin as a Therapeutic Agent \u300d<\/span><\/p>\n

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