{"id":6269,"date":"2018-11-13T00:03:02","date_gmt":"2018-11-12T15:03:02","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=6269"},"modified":"2020-01-10T08:39:39","modified_gmt":"2020-01-09T23:39:39","slug":"post-6269","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=6269","title":{"rendered":"LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u65b9\u304c\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u4f4e\u3044"},"content":{"rendered":"<p>\u8a8d\u77e5\u75c7\u306f\u3069\u3093\u3069\u3093\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f3\u578b\u7cd6\u5c3f\u75c5\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u8840\u7cd6\u5024\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u8a71\u3068\u306f\u5225\u306b\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306e\u95a2\u9023\u306e\u8a71\u984c\u3067\u3059\u3002<\/p>\n<p>\u8133\u306f\u975e\u5e38\u306b\u591a\u304f\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u542b\u3093\u3067\u3044\u307e\u3059\u3002\u5168\u3066\u306e\u7d30\u80de\u819c\u306e\u69cb\u6210\u6210\u5206\u3067\u3059\u304b\u3089\u3001\u3082\u3061\u308d\u3093\u8133\u306e\u7d30\u80de\u819c\u3082\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u305f\u3063\u3077\u308a\u3067\u3059\u3002\u3067\u3059\u304b\u3089\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u4f4e\u3044\u3053\u3068\u306f\u6c7a\u3057\u3066\u8133\u306b\u826f\u3044\u3068\u306f\u601d\u3048\u307e\u305b\u3093\u3002<\/p>\n<p>\u4eca\u56de\u306f\u540c\u3058\u30a2\u30b8\u30a2\u4eba\u306e\u4e2d\u56fd\u3067\u306e\u7814\u7a76\u3067\u3059\u300265\u6b73\u4ee5\u4e0a\u306e1,889\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u3046\u306186\u4f8b\u306f\u8a8d\u77e5\u75c7\u3001603\u4f8b\u306fMCI\uff08\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff09\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u4eba\u305f\u3061\u3068\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u95a2\u9023\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"6397\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=6397\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?fit=1145%2C599&amp;ssl=1\" data-orig-size=\"1145,599\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;Wei Deng and Ding Ding&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;Background: The relationship between cholesterol and cognitive function is unclear from the previous studies.&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;High Low-Density Lipoprotein Cholesterol Inversely Relates to De&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"High Low-Density Lipoprotein Cholesterol Inversely Relates to De\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Background: The relationship between cholesterol and cognitive function is unclear from the previous studies.&lt;\/p&gt;\n\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?fit=300%2C157&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?fit=640%2C335&amp;ssl=1\" class=\"size-medium wp-image-6397\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?resize=300%2C157\" alt=\"\" width=\"300\" height=\"157\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?resize=300%2C157&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?resize=768%2C402&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?resize=1024%2C536&amp;ssl=1 1024w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?resize=320%2C167&amp;ssl=1 320w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/705e2519ebba82ec630aaa0390181cea.jpg?w=1145&amp;ssl=1 1145w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306fTC\uff08\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff09\u3001LDL-C\uff08LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff09\u3001HDL-C\uff08HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff09\u3067\u305d\u308c\u305e\u308c\u4f4e\u5024\u3001\u4e2d\u7a0b\u5ea6\u3001\u9ad8\u5024\u306e\u30aa\u30c3\u30ba\u6bd4\uff08OR\uff09\u3092\u793a\u3057\u3001\u6b63\u5e38\u306e\u4eba\u306b\u5bfe\u3057MCI\u3068\u3001\u6b63\u5e38\u306e\u4eba\u306b\u5bfe\u3057Dementia\uff08\u8a8d\u77e5\u75c7\uff09\u3092\u6bd4\u8f03\u3057\u3066\u3044\u307e\u3059\u3002\u5de6\u5074\u3068\u53f3\u5074\u306e\u9055\u3044\u306f\u5de6\u304c\u8abf\u6574\u3055\u308c\u3066\u3044\u306a\u3044\u7d71\u8a08\u3067\u3001\u53f3\u5074\u304c\u8abf\u6574\u3057\u305f\u5f8c\u306e\u3082\u306e\u3067\u3059\u3002OR\u306f\u4f4e\u3044\u307b\u3069\u8a8d\u77e5\u75c7\u3084MCI\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u4f4e\u3044\u3068\u8003\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>TC\u3067\u898b\u308b\u3068\u6709\u610f\u5dee\u306f\u7121\u3044\u3082\u306e\u306e\u3001\u8a8d\u77e5\u75c7\u306fHigh\uff08\u9ad8\u5024\uff09\u7fa4\u3067OR\u304c\u4f4e\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3055\u3089\u306bLDL-C\u3092\u898b\u308b\u3068\u6709\u610f\u306b\u8a8d\u77e5\u75c7\u306fHigh\uff08\u9ad8\u5024\uff09\u7fa4\u3067OR\u304c\u4f4e\u304f0.5\u3067\u3059\u3002HDL-C\u3068\u306e\u95a2\u9023\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3002MCI\u306f\u3069\u308c\u3082\u95a2\u9023\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306b\u8a8d\u77e5\u75c7\u306e\u4fdd\u8b77\u4f5c\u7528\u304c\u3042\u308b\u306e\u304b\u3069\u3046\u304b\u306f\u306f\u3063\u304d\u308a\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u5c11\u306a\u304f\u3068\u3082\u9ad8\u9f62\u8005\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u4f4e\u4e0b\u3055\u305b\u308b\u3079\u304d\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u8133\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0d\u8db3\u3084\u7523\u751f\u306e\u963b\u5bb3\u304c\u795e\u7d4c\u5909\u6027\u3092\u4fc3\u9032\u3057\u305f\u308a\u3001\u795e\u7d4c\u7d30\u80de\u306e\u6b7b\u3092\u4fc3\u9032\u3057\u305f\u308a\u3059\u308b\u3068\u3044\u3046\u7814\u7a76\u3082\u3042\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u30b9\u30bf\u30c1\u30f3\u306f\u8133\u306b\u3068\u3063\u3066\u6709\u5bb3\u3067\u3059\u3002<\/p>\n<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=5211\" target=\"_blank\" rel=\"noopener noreferrer\">\u5375\u3092\u98df\u3079\u3088\u3046\uff01\u8a8d\u77e5\u75c7\u306e\u89b3\u70b9\u304b\u3089<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u5375\u3092\u98df\u3079\u3066\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u6442\u53d6\u91cf\u304c\u591a\u3044\u307b\u3069\u8a8d\u77e5\u6a5f\u80fd\u304c\u5411\u4e0a\u3057\u305f\u3068\u3044\u3046\u7814\u7a76\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=5807\" target=\"_blank\" rel=\"noopener noreferrer\">LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u306e\u6709\u76ca\u6027\u306e\u8a3c\u62e0\u306f\u306a\u3044\uff01<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4e0b\u3052\u308b\u6709\u76ca\u6027\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u4f55\u3057\u308d\u3001\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=3229\" target=\"_blank\" rel=\"noopener noreferrer\">\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306b\u4e00\u559c\u4e00\u6182\u3057\u306a\u3044\u305f\u3081\u306b<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u3044\u307b\u3069\u9577\u751f\u304d\u306a\u306e\u3067\u3059\u304b\u3089\u3002<\/p>\n<p>\u8133\u306e\u3053\u3068\u3092\u8003\u3048\u305f\u3089\u3001\u9ad8\u9f62\u306b\u306a\u3063\u305f\u3089\u52c7\u6c17\u3092\u51fa\u3057\u3066\u30b9\u30bf\u30c1\u30f3\u306f\u6b62\u3081\u305f\u65b9\u304c\u826f\u3044\u3068\u601d\u3044\u307e\u3059\u3002\uff08\u9ad8\u9f62\u306b\u306a\u3089\u306a\u304f\u3066\u3082\u3067\u3059\u304c\uff09\u305d\u3057\u3066\u3001\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=6113\" target=\"_blank\" rel=\"noopener noreferrer\">\u98df\u4e8b\u3092\u5909\u3048\u308c\u3070\u8a8d\u77e5\u75c7\u3092\u9006\u8ee2\u3067\u304d\u308b\u3000\u8a8d\u77e5\u75c7\u9006\u8ee2\u30d7\u30ed\u30b8\u30a7\u30af\u30c8<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u98df\u4e8b\u3092\u5909\u3048\u3066\u7cd6\u8cea\u5236\u9650\u3092\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u3088\u304f\u81ea\u5206\u3067\u8003\u3048\u3066\u5224\u65ad\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\">\u300cHigh Low-Density Lipoprotein Cholesterol Inversely Relates to Dementia in Community-Dwelling Older Adults: The Shanghai Aging Study\u300d<\/span><\/p>\n<p><span style=\"color: #0000ff;\">\u300c\u9ad8LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3001\u5730\u57df\u4f4f\u5c45\u9ad8\u9f62\u8005\u306e\u8a8d\u77e5\u75c7\u3068\u9006\u76f8\u95a2\u3059\u308b\uff1a\u4e0a\u6d77\u9ad8\u9f62\u5316\u7814\u7a76\u300d\uff08\u539f\u6587\u306f<a style=\"color: #0000ff;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2018.00952\/full\" target=\"_blank\" rel=\"noopener noreferrer\">\u3053\u3053<\/a>\uff09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8a8d\u77e5\u75c7\u306f\u3069\u3093\u3069\u3093\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f3\u578b\u7cd6\u5c3f\u75c5\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u8840\u7cd6\u5024\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u8a71\u3068\u306f\u5225\u306b\u3001\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306e\u95a2\u9023\u306e\u8a71\u984c\u3067\u3059\u3002 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