{"id":6545,"date":"2018-12-11T00:07:31","date_gmt":"2018-12-10T15:07:31","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=6545"},"modified":"2018-12-11T00:07:39","modified_gmt":"2018-12-10T15:07:39","slug":"post-6545","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=6545","title":{"rendered":"PPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u306f\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u304b\u3082\u3057\u308c\u306a\u3044"},"content":{"rendered":"<p>\u73fe\u5728\u3001\u3069\u308c\u307b\u3069\u591a\u304f\u306e\u4eba\u304cPPI\uff08\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff09\u3092\u9577\u671f\u306b\u4f7f\u7528\u3057\u3066\u3044\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u3067\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u304c\u51e6\u65b9\u3055\u308c\u307e\u3059\u304c\u3001PPI\u306f\u3053\u306e\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u52b9\u679c\u3092\u6e1b\u5f31\u3059\u308b\u3088\u3046\u3067\u3059\u3002<\/p>\n<p>\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u306b\u3088\u308a\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3001\u9000\u9662\u6642\u307e\u305f\u306f\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u6642\u306b\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u3068PPI\u3092\u51e6\u65b9\u3057\u305f\u60a3\u8005\u306e\u5168\u6b7b\u4ea1\u7387\u304a\u3088\u3073\u518d\u767a\u6025\u6027\u51a0\u52d5\u8108\u75c7\u5019\u7fa4\u306e\u7d2f\u7a4d\u30ea\u30b9\u30af\u3092\u4e0b\u306b\u793a\u3057\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><a 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data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/1d0415978b35200e8c97344567c3e257.png?fit=300%2C207&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/1d0415978b35200e8c97344567c3e257.png?fit=640%2C441&amp;ssl=1\" class=\"alignnone size-medium wp-image-6547\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/1d0415978b35200e8c97344567c3e257.png?resize=300%2C207\" alt=\"\" width=\"300\" height=\"207\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/1d0415978b35200e8c97344567c3e257.png?resize=300%2C207&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/1d0415978b35200e8c97344567c3e257.png?resize=320%2C220&amp;ssl=1 320w, 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rel=\"noopener\">\u3053\u306e\u8ad6\u6587<\/a>\u3088\u308a\uff09<\/p>\n<p>\u3069\u3061\u3089\u306e\u85ac\u3082\u4f7f\u7528\u3057\u3066\u3044\u306a\u3044\u7fa4\u304c\u6700\u3082\u30ea\u30b9\u30af\u304c\u9ad8\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u3092\u98f2\u3093\u3067\u3044\u3066\u3001PPI\u3092\u4f75\u7528\u3057\u3066\u3044\u305f\u5834\u5408\u3068\u4f75\u7528\u3057\u3066\u3044\u306a\u3044\u5834\u5408\u3067\u306f\u3001\u6709\u610f\u306b\u4f75\u7528\u3057\u3066\u3044\u305f\u65b9\u304c\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u305d\u308c\u3067\u306f\u3001\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u3067\u306f\u306a\u304f\u3001\u4e00\u822c\u306e\u96c6\u56e3\u3067\u306fPPI\u3068\u5fc3\u7b4b\u6897\u585e\u306e\u95a2\u9023\u306f\u3069\u3046\u306a\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u80c3\u98df\u9053\u9006\u6d41\u75c7\uff08GERD\uff09\u3067PPI\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u4eba\u3092\u5bfe\u8c61\u306b\u5fc3\u7b4b\u6897\u585e\u3068\u306e\u95a2\u9023\u3092\u5206\u6790\u3057\u305f\u7814\u7a76\u3067\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\uff09<\/p>\n<p>&nbsp;<\/p>\n<p><a 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data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/bd74f6fd8ab06dbbca8d4719fa7f670e.png?fit=300%2C235&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/bd74f6fd8ab06dbbca8d4719fa7f670e.png?fit=640%2C503&amp;ssl=1\" class=\"alignnone size-medium wp-image-6552\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/bd74f6fd8ab06dbbca8d4719fa7f670e.png?resize=300%2C235\" alt=\"\" width=\"300\" height=\"235\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/bd74f6fd8ab06dbbca8d4719fa7f670e.png?resize=300%2C235&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/bd74f6fd8ab06dbbca8d4719fa7f670e.png?resize=768%2C603&amp;ssl=1 768w, 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href=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"6551\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=6551\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?fit=1697%2C1220&amp;ssl=1\" data-orig-size=\"1697,1220\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"PPI\u5fc3\u7b4b\u6897\u585ejournal.pone.0124653.g002 (1)\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?fit=300%2C216&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?fit=640%2C460&amp;ssl=1\" class=\"alignnone size-medium wp-image-6551\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?resize=300%2C216\" alt=\"\" width=\"300\" height=\"216\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?resize=300%2C216&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?resize=768%2C552&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?resize=1024%2C736&amp;ssl=1 1024w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?resize=320%2C230&amp;ssl=1 320w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?w=1697&amp;ssl=1 1697w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2018\/11\/69eb06028fb94b7a780e1d338df059f3.png?w=1280 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u672b\u68a2\u52d5\u8108\u75be\u60a3\u306e\u907a\u4f1d\u7684\u6c7a\u5b9a\u56e0\u5b50\uff08GenePAD\uff09\u7814\u7a76\u306e\u96c6\u56e3\u3067\u5206\u6790\u3057\u305f\u751f\u5b58\u5206\u6790\u3067\u3059\u3002\uff08\u7533\u3057\u8a33\u3042\u308a\u307e\u305b\u3093\u304c\u3053\u306eGenePAD\u3068\u3044\u3046\u7814\u7a76\u306e\u8a73\u7d30\u306f\u77e5\u308a\u307e\u305b\u3093\uff09PPI\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3068\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f122\uff05\u5897\u52a0\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>PPI\u306e\u4f7f\u7528\u304c\u300155\u6b73\u4ee5\u4e0b\u3068\u3044\u3046\u82e5\u5e74\u8005\u304a\u3088\u3073\u6297\u8840\u5c0f\u677f\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u306a\u3044\u4eba\u3005\u3092\u542b\u3080\u4e00\u822c\u96c6\u56e3\u3067\u3001\u5fc3\u7b4b\u6897\u585e\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002PPI\u304c\u3001\u8840\u5c0f\u677f\u51dd\u96c6\u3092\u76f4\u63a5\u7684\u306b\u306f\u4f34\u308f\u306a\u3044\u672a\u77e5\u306e\u6a5f\u5e8f\u306b\u3088\u3063\u3066\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u3066\u3044\u308b\u306e\u3067\u306f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a href=\"http:\/\/promea2014.com\/blog\/?p=6130\" target=\"_blank\" rel=\"noopener\">\u7cd6\u8cea\u5236\u9650\u3068\u9006\u6d41\u6027\u98df\u9053\u708e\u306e\u6539\u5584<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u80c3\u98df\u9053\u9006\u6d41\u75c7\uff08GERD\uff09\u3067PPI\u3092\u4f7f\u7528\u3059\u308b\u5fc5\u8981\u306f\u7121\u304f\u3001\u7cd6\u8cea\u5236\u9650\u306e\u65b9\u304c\u52b9\u679c\u7684\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u305d\u308c\u3067\u3082\u307e\u3060PPI\u3092\u98f2\u307f\u307e\u3059\u304b\uff1f<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\">\u300cProton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population\u300d<\/span><\/p>\n<p><span style=\"color: #0000ff;\">\u300c\u4e00\u822c\u96c6\u56e3\u306b\u304a\u3051\u308b\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\u306e\u4f7f\u7528\u3068\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u300d\uff08\u539f\u6587\u306f<a style=\"color: 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