{"id":8148,"date":"2019-05-24T06:49:00","date_gmt":"2019-05-23T21:49:00","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=8148"},"modified":"2020-01-05T14:17:27","modified_gmt":"2020-01-05T05:17:27","slug":"post-8148","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=8148","title":{"rendered":"\u3053\u3093\u306a\u306b\u6016\u3044\u8102\u80aa\u809d"},"content":{"rendered":"<p><\/p>\n<p>\u8102\u80aa\u809d\u3092\u4fae\u3063\u3066\u3044\u308b\u4eba\u306f\u975e\u5e38\u306b\u591a\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u305f\u3060\u306e\u80a5\u6e80\u306e\u5fb4\u5019\u306e\u3088\u3046\u306b\u601d\u3063\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u306f\u6700\u3082\u983b\u7e41\u306b\u8a8d\u3081\u3089\u308c\u308b\u3001\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306e\u75c5\u614b\u306e\u4e00\u3064\u3067\u3059\u3002\u73fe\u5728\u65e5\u672c\u4eba\u306e25\uff05\u4ee5\u4e0a\u306b\u8a8d\u3081\u3089\u308c\u308b\u3068\u3082\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u306e10\uff5e30\uff05\u306f\u3088\u308a\u60aa\u3044\u72b6\u614b\u306e\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u708e\uff08NASH\uff09\u306b\u9032\u884c\u3057\u307e\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u305d\u306e\u5148\u306b\u306f\u809d\u786c\u5909\u3084\u809d\u81d3\u304c\u3093\u304c\u5f85\u3061\u53d7\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u4eca\u56de\u306e\u7814\u7a76\u306f\u975e\u5e38\u306b\u5927\u898f\u6a21\u3067\u3059\u3002\u30e8\u30fc\u30ed\u30c3\u30d1\u306e1,800\u4e07\u4eba\u306e\u60a3\u8005\u306e\u30c7\u30fc\u30bf\u3092\u5206\u6790\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3092\u898b\u308b\u3068\u3001\u8102\u80aa\u809d\u3068\u305d\u306e\u5f8c\u306e\u809d\u708e\u304c\u3069\u308c\u307b\u3069\u6016\u3044\u3082\u306e\u306a\u306e\u304b\u304c\u308f\u304b\u308a\u307e\u3059\u3002\uff08\u56f3\u306f\u539f\u6587\u3088\u308a\u3001\u8868\u306f\u539f\u6587\u3088\u308a\u6539\u5909\uff09<\/p>\n<p><\/p>\n<p><\/p>\n<figure class=\"wp-block-image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"520\" data-attachment-id=\"8185\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=8185\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?fit=785%2C638&amp;ssl=1\" data-orig-size=\"785,638\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u8102\u80aa\u809d\u304c\u309312916_2019_1321_Fig1_HTML\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?fit=300%2C244&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?fit=640%2C520&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?resize=640%2C520\" alt=\"\" class=\"wp-image-8185\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?w=785&amp;ssl=1 785w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?resize=300%2C244&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?resize=768%2C624&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/a4bb6f71aea2cad92355ed12cbf43397.png?resize=320%2C260&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure>\n<p><\/p>\n<p><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u809d\u786c\u5909\u306b\u306a\u308b\u30ea\u30b9\u30af\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002NAFLD\u306f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u3001NASH\u306f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u708e\u3067\u3059\u3002NAFLD\u307e\u305f\u306fNASH\u304c\u3042\u308b\u3068\u809d\u786c\u5909\u306b\u306a\u308b\u30ea\u30b9\u30af\u306f\u306a\u3093\u3068\u30014.73\u500d\u3067\u3059\u3002NAFLD\u3060\u3051\u3092\u5358\u72ec\u3067\u898b\u3066\u307f\u308b\u3068\u3001\u809d\u786c\u5909\u306e\u30ea\u30b9\u30af\u306f5.83\u500d\u3001NASH\u5358\u72ec\u3067\u306f\u306a\u3093\u3068\u306a\u3093\u3068\u300122.67\u500d\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<figure class=\"wp-block-image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"297\" data-attachment-id=\"8186\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=8186\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?fit=785%2C364&amp;ssl=1\" data-orig-size=\"785,364\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u8102\u80aa\u809d\u304c\u309312916_2019_1321_Fig2_HTML\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?fit=300%2C139&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?fit=640%2C297&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?resize=640%2C297\" alt=\"\" class=\"wp-image-8186\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?w=785&amp;ssl=1 785w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?resize=300%2C139&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?resize=768%2C356&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/05\/7b8e6cbe6fb0e47b7db927d7102c7374.png?resize=320%2C148&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure>\n<p><\/p>\n<p><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u809d\u81d3\u304c\u3093\u306e\u30ea\u30b9\u30af\u3067\u3059\u3002NAFLD\u307e\u305f\u306fNASH\u304c\u3042\u308b\u3068\u809d\u81d3\u304c\u3093\u306b\u306a\u308b\u30ea\u30b9\u30af\u306f\u306a\u3093\u3068\u30013.51\u500d\u3067\u3059\u3002NAFLD\u3060\u3051\u3092\u5358\u72ec\u3067\u898b\u3066\u307f\u308b\u3068\u3001\u809d\u786c\u5909\u306e\u30ea\u30b9\u30af\u306f3.15\u500d\u3001NASH\u5358\u72ec\u3067\u306f\u306a\u3093\u3068\u306a\u3093\u3068\u30018.02\u500d\u3067\u3059\u3002 \u6050\u308d\u3057\u3044\uff5e\uff01<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u3055\u3089\u306b\u6050\u308d\u3057\u3044\u3053\u3068\u306bNAFLD\u304c\u3042\u308b\u3068\u809d\u786c\u5909\u3068\u8a3a\u65ad\u3055\u308c\u308b\u307e\u3067\u306b\u4e2d\u592e\u5024\u30672\uff5e2.9\u5e74\u3068\u3044\u3046\u77ed\u671f\u9593\u3067\u3042\u308a\u3001NASH\u304c\u3042\u308b\u3068\u809d\u786c\u5909\u3068\u8a3a\u65ad\u3055\u308c\u308b\u307e\u3067\u306b0.5\uff5e3\u5e74\u3068\u3044\u3046\u77ed\u3055\u3067\u3059\u3002<\/p>\n<p><\/p>\n<div class=\"CaptionContent\">\n<p class=\"SimplePara\">\u00a0<\/p>\n<\/div>\n<div class=\"Table\">\n<table style=\"height: 524px; width: 527px;\" border=\"1\">\n<colgroup>\n<col \/>\n<col char=\"(\" \/>\n<col char=\"(\" \/><\/colgroup>\n<thead>\n<tr class=\"header\" style=\"height: 93px;\">\n<th style=\"height: 93px; width: 286.4px;\">\u00a0<\/th>\n<th style=\"height: 93px; width: 233.6px;\" char=\"(\">\n<p class=\"SimplePara\">HR\uff0895\uff05CI\uff09<\/p>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"noclass\" style=\"height: 93px;\">\n<td style=\"height: 93px; width: 286.4px;\">\n<p class=\"SimplePara\">\u73fe\u5728\u306e\u55ab\u7159<\/p>\n<\/td>\n<td style=\"height: 93px; width: 233.6px;\" char=\"(\">\n<p class=\"SimplePara\">1.50\uff081.41; 1.60\uff09<\/p>\n<\/td>\n<\/tr>\n<tr class=\"noclass\" style=\"height: 64px;\">\n<td style=\"height: 64px; width: 286.4px;\">\n<p class=\"SimplePara\">\u5e74\u9f62\uff08\u6b73\uff09<\/p>\n<\/td>\n<td style=\"height: 64px; width: 233.6px;\" char=\"(\">\n<p class=\"SimplePara\">1.04\uff081.03; 1.04\uff09<\/p>\n<\/td>\n<\/tr>\n<tr class=\"noclass\" style=\"height: 93px;\">\n<td style=\"height: 93px; width: 286.4px;\">\n<p class=\"SimplePara\">\u7cd6\u5c3f\u75c5\u306e\u65e2\u5f80<\/p>\n<\/td>\n<td style=\"height: 93px; width: 233.6px;\" char=\"(\">\n<p class=\"SimplePara\"><span style=\"color: #ff0000;\">2.92<\/span>\uff082.76; 3.08\uff09<\/p>\n<\/td>\n<\/tr>\n<tr class=\"noclass\" style=\"height: 93px;\">\n<td style=\"height: 93px; width: 286.4px;\">\n<p class=\"SimplePara\">\u9ad8\u8840\u5727\u306e\u65e2\u5f80<\/p>\n<\/td>\n<td style=\"height: 93px; width: 233.6px;\" char=\"(\">\n<p class=\"SimplePara\">1.07\uff081.01; 1.13\uff09<\/p>\n<\/td>\n<\/tr>\n<tr class=\"noclass\" style=\"height: 66px;\">\n<td style=\"height: 66px; width: 286.4px;\">\n<p class=\"SimplePara\">BMI<\/p>\n<\/td>\n<td style=\"height: 66px; width: 233.6px;\" char=\"(\">\n<p class=\"SimplePara\">1.04\uff081.03; 1.04\uff09<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p><\/p>\n<p>\u4e0a\u306e\u8868NAFLD\u3084NASH\u304c\u3042\u308b\u5834\u5408\u306b\u809d\u786c\u5909\u3084\u809d\u81d3\u304c\u3093\u306b\u306a\u308b\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u56e0\u5b50\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002\u55ab\u7159\u306f1.5\u500d\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u4f55\u3068\u8a00\u3063\u3066\u3082\u7cd6\u5c3f\u75c5\u306e\u65e2\u5f80\u304c\u3042\u308b\u30682.92\u500d\u306b\u3082\u306a\u308a\u307e\u3059\u3002\u7cd6\u8cea\u904e\u5270\u75c7\u5019\u7fa4\u306e\u6050\u308d\u3057\u3055\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u4ee5\u524d\u306e\u8a18\u4e8b\u300c<a rel=\"noreferrer noopener\" aria-label=\"\u8102\u80aa\u809d\u306f\u305f\u3060\u306e\u80a5\u6e80\u306e\u75c7\u72b6\u3067\u306f\u306a\u3044 (opens in a new tab)\" href=\"http:\/\/promea2014.com\/blog\/?p=2547\" target=\"_blank\">\u8102\u80aa\u809d\u306f\u305f\u3060\u306e\u80a5\u6e80\u306e\u75c7\u72b6\u3067\u306f\u306a\u3044<\/a>\u300d\u3067\u3082\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u8102\u80aa\u809d\u306f\u4fae\u308c\u307e\u305b\u3093\u3002\u305d\u3057\u3066\u3001\u300c<a rel=\"noreferrer noopener\" aria-label=\"\u7cd6\u8cea\u5236\u9650\u306f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u3092\u5287\u7684\u306b\u6539\u5584\u3059\u308b (opens in a new tab)\" href=\"http:\/\/promea2014.com\/blog\/?p=7401\" target=\"_blank\">\u7cd6\u8cea\u5236\u9650\u306f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u3092\u5287\u7684\u306b\u6539\u5584\u3059\u308b<\/a>\u300d\u300c<a rel=\"noreferrer noopener\" aria-label=\"\u6c5f\u90e8\u5eb7\u4e8c\u5148\u751f\u300c\u5185\u81d3\u8102\u80aa\u304c\u30b9\u30c8\u30f3\u3068\u843d\u3061\u308b\u98df\u4e8b\u8853\u300d\u304c\u767a\u58f2\u306b\u306a\u308a\u307e\u3057\u305f (opens in a new tab)\" href=\"http:\/\/promea2014.com\/blog\/?p=8053\" target=\"_blank\">\u6c5f\u90e8\u5eb7\u4e8c\u5148\u751f\u300c\u5185\u81d3\u8102\u80aa\u304c\u30b9\u30c8\u30f3\u3068\u843d\u3061\u308b\u98df\u4e8b\u8853\u300d\u304c\u767a\u58f2\u306b\u306a\u308a\u307e\u3057\u305f<\/a>\u300d\u306a\u3069\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u7cd6\u8cea\u5236\u9650\u3067\u8102\u80aa\u809d\u306f\u5287\u7684\u306b\u6539\u5584\u3057\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u8102\u80aa\u809d\u304c\u308f\u304b\u3063\u305f\u3089\u8e8a\u8e87\u306a\u304f\u7cd6\u8cea\u5236\u9650\u3067\u3057\u3087\u3046\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p><\/p>\n<p><\/p>\n<p class=\"has-text-color has-vivid-cyan-blue-color\">\u300cRisks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts\u300d<\/p>\n<p><\/p>\n<p><\/p>\n<p class=\"has-text-color has-vivid-cyan-blue-color\">\u300c\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u809d\u3068\u8a3a\u65ad\u3055\u308c\u305f\u6210\u4eba\u306b\u304a\u3051\u308b\u809d\u786c\u5909\u304a\u3088\u3073\u809d\u7d30\u80de\u304c\u3093\u8a3a\u65ad\u306e\u30ea\u30b9\u30af\u3068\u81e8\u5e8a\u7684\u4e88\u6e2c\u56e0\u5b50\uff1a4\u3064\u306e\u30e8\u30fc\u30ed\u30c3\u30d1\u306e\u30b3\u30db\u30fc\u30c8\u306b\u304a\u3051\u308b1,800\u4e07\u4eba\u306e\u60a3\u8005\u306e\u5b9f\u4e16\u754c\u7814\u7a76\u300d\uff08\u539f\u6587\u306f<a rel=\"noreferrer noopener\" aria-label=\"\u3053\u3053 (opens in a new tab)\" href=\"https:\/\/bmcmedicine.biomedcentral.com\/articles\/10.1186\/s12916-019-1321-x\" 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