{"id":9288,"date":"2019-08-08T00:00:50","date_gmt":"2019-08-07T15:00:50","guid":{"rendered":"http:\/\/promea2014.com\/blog\/?p=9288"},"modified":"2020-01-05T14:15:14","modified_gmt":"2020-01-05T05:15:14","slug":"post-9288","status":"publish","type":"post","link":"https:\/\/promea2014.com\/blog\/?p=9288","title":{"rendered":"\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306b\u3088\u308b\u6709\u5bb3\u6027\u306f\uff1f\u3000\u305d\u306e3\u3000\u30a2\u30b9\u30ea\u30fc\u30c8"},"content":{"rendered":"<p><\/p>\n<p>\u524d\u56de\u306e\u8a18\u4e8b\u300c<a aria-label=\"\u305d\u306e2 (opens in a new tab)\" rel=\"noreferrer noopener\" href=\"http:\/\/promea2014.com\/blog\/?p=9265\" target=\"_blank\">\u305d\u306e2<\/a>\u300d\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u3068mTOR\u306e\u6d3b\u6027\u5316\u306b\u3064\u3044\u3066\u66f8\u304d\u307e\u3057\u305f\u3002\u305d\u306e\u6700\u5f8c\u306e\u65b9\u3067\u6700\u8fd1\u82e5\u3044\u30a2\u30b9\u30ea\u30fc\u30c8\u306b\u304c\u3093\u304c\u591a\u3044\u306e\u3067\u306f\uff1f\u3068\u3044\u3046\u3053\u3068\u3092\u66f8\u304d\u307e\u3057\u305f\u3002\u305f\u3060\u3001\u3053\u308c\u306f\u79c1\u306e\u5370\u8c61\u3067\u3042\u308a\u3001\u6700\u8fd1\u306f\u304c\u3093\u306b\u306a\u3063\u305f\u3053\u3068\u3092\u516c\u8868\u3059\u308b\u4eba\u304c\u5897\u3048\u305f\u304b\u3089\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u5b9f\u969b\u306b\u30c7\u30fc\u30bf\u306f\u3042\u307e\u308a\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u6700\u8fd1\u30e1\u30b8\u30e3\u30fc\u30ea\u30fc\u30ac\u30fc\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u304c\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u305d\u308c\u306b\u3088\u308b\u3068\u3001\u5168\u4f53\u7684\u306b\u6b7b\u4ea1\u7387\u306f\u4e00\u822c\u306e\u4eba\u53e3\u3068\u6bd4\u8f03\u3057\u3066\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u304c\u3093\u306b\u3088\u308b\u6b7b\u4ea1\u7387\u306f\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u304c\u3093\u5168\u4f53\u3068\u3057\u3066\u306f\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f\u308f\u305a\u304b\u306b8\uff05\u5897\u3067\u3057\u305f\u304c\u3001\u80ba\u304c\u3093\u306713\uff05\u5897\uff08\u80ba\u304c\u3093\u306f\u6709\u610f\u5dee\u306a\u3057\uff09\u3001\u8840\u6db2\u306e\u304c\u3093\u304c22\uff05\u5897\u3001\u76ae\u819a\u306e\u304c\u3093\u304c53\uff05\u5897\u3067\u3059\u3002\u76ae\u819a\u304c\u3093\u306b\u3064\u3044\u3066\u306f\u592a\u967d\u3092\u983b\u7e41\u306b\u9577\u6642\u9593\u6d74\u3073\u3066\u3044\u308b\u306e\u3067\u3001\u305d\u306e\u5f71\u97ff\u3082\u3042\u308b\u3067\u3057\u3087\u3046\u3002\u8840\u6db2\u306e\u304c\u3093\u306f\u975e\u5e38\u306b\u6c17\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u305d\u3082\u305d\u3082\u3001\u30d7\u30ed\u306e\u30b9\u30dd\u30fc\u30c4\u9078\u624b\u306b\u306a\u308b\u3088\u3046\u306a\u4eba\u306f\u3001\u3082\u3068\u3082\u3068\u5065\u5eb7\u3067\u3042\u308b\u3053\u3068\u306f\u660e\u767d\u3067\u3057\u3087\u3046\u3002\u30d7\u30ed\u306b\u306a\u3063\u305f\u5f8c\u3082\u6d3b\u8e8d\u3067\u304d\u308b\u4f53\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b\u3001\u5065\u5eb7\u7684\u306a\u3053\u3068\u3092\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u591a\u3044\u3068\u601d\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3001\u524d\u56de\u306e\u8a18\u4e8b\u300c<a rel=\"noreferrer noopener\" aria-label=\"\u904b\u52d5\u306f\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b (opens in a new tab)\" href=\"http:\/\/promea2014.com\/blog\/?p=9271\" target=\"_blank\">\u904b\u52d5\u306f\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b<\/a>\u300d\u3067\u66f8\u3044\u305f\u3088\u3046\u306b\u3001\u904b\u52d5\u306f\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002\u8840\u6db2\u306e\u304c\u3093\u3067\u3042\u308b\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u306b\u95a2\u3057\u3066\u306f20\uff05\u4f4e\u4e0b\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u30e1\u30b8\u30e3\u30fc\u30ea\u30fc\u30ac\u30fc\u3067\u306f\u4e00\u822c\u4eba\u3088\u308a22\uff05\u5897\u3067\u3042\u308b\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u304b\u306a\u308a\u306e\u5897\u52a0\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u6fc0\u3057\u3044\u904b\u52d5\u306f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u5897\u52a0\u3055\u305b\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u304c\u3001\u5408\u7406\u7684\u306a\u7df4\u7fd2\u3092\u3059\u308b\u30e1\u30b8\u30e3\u30fc\u3067\u306f\u305d\u3053\u307e\u3067\u306e\u7df4\u7fd2\u91cf\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3082\u91ce\u7403\u306f\u7279\u306b\u6fc0\u3057\u3044\u904b\u52d5\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30d4\u30c3\u30c1\u30e3\u30fc\u4ee5\u5916\u306f\u8a66\u5408\u306e\u307b\u3068\u3093\u3069\u306f\u4f11\u307f\u3067\u3059\u304b\u3089\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u3082\u3061\u308d\u3093\u3001\u539f\u56e0\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u79c1\u306f\u73fe\u5728\u306e\u7b4b\u30c8\u30ec\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u306e\u666e\u53ca\u304c\u3082\u3057\u304b\u3057\u305f\u3089\u304c\u3093\u3092\u5897\u52a0\u3055\u305b\u3066\u3044\u308b\u306e\u3067\u306f\uff1f\u3068\u5371\u60e7\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u56f3\u306f<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25417152\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"\u3053\u306e\u8ad6\u6587 (opens in a new tab)\">\u3053\u306e\u8ad6\u6587<\/a>\u3088\u308a\uff09<\/p>\n<p><\/p>\n<p><\/p>\n<figure class=\"wp-block-image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"628\" height=\"818\" data-attachment-id=\"9217\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=9217\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?fit=628%2C818&amp;ssl=1\" data-orig-size=\"628,818\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u904b\u52d5\u3068mtor\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?fit=230%2C300&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?fit=628%2C818&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?resize=628%2C818\" alt=\"\" class=\"wp-image-9217\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?w=628&amp;ssl=1 628w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?resize=230%2C300&amp;ssl=1 230w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/e49a834a8c5ac42aee828e509c3399a8.jpg?resize=320%2C417&amp;ssl=1 320w\" sizes=\"auto, (max-width: 628px) 100vw, 628px\" \/><\/figure>\n<p><\/p>\n<p><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u5de6\u304c\u30d1\u30ef\u30fc\u7cfb\u306e\u904b\u52d5\u3001\u7b4b\u30c8\u30ec\u306a\u3069\u306b\u3088\u308b\u3001\u69d8\u3005\u306a\u4ee3\u8b1d\u306e\u6d41\u308c\u3092\u793a\u3057\u3066\u304a\u308a\u3001\u53f3\u5074\u304c\u6301\u4e45\u7cfb\u306e\u904b\u52d5\u306e\u6d41\u308c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u7b4b\u30c8\u30ec\u306a\u3069\u306fmTOR\u3092\u6d3b\u6027\u5316\u3055\u305b\u3001\u7b4b\u8089\u306e\u80a5\u5927\u304c\u8d77\u3053\u308a\u307e\u3059\u304c\u3001\u6301\u4e45\u7cfb\u306e\u904b\u52d5\u306fAMPK\u304c\u6d3b\u6027\u5316\u3057\u3001mTOR\u306f\u6291\u5236\u3055\u308c\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5897\u6b96\u304c\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u3082\u3061\u308d\u3093\u3001\u6301\u4e45\u7cfb\u306e\u904b\u52d5\u3067\u3082\u904b\u52d5\u3057\u306a\u3044\u3053\u3068\u306b\u6bd4\u3079\u308c\u3070mTOR\u306f\u5897\u52a0\u3057\u307e\u3059\u3002\uff08\u56f3\u306f<a rel=\"noreferrer noopener\" aria-label=\"\u3053\u306e\u8ad6\u6587 (opens in a new tab)\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23802289\" target=\"_blank\">\u3053\u306e\u8ad6\u6587<\/a>\u3088\u308a\uff09<\/p>\n<p><\/p>\n<p><\/p>\n<figure class=\"wp-block-image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"366\" height=\"274\" data-attachment-id=\"9317\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=9317\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?fit=366%2C274&amp;ssl=1\" data-orig-size=\"366,274\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;Yasuyuki&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1565219451&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u904b\u52d5mTOR\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?fit=300%2C225&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?fit=366%2C274&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?resize=366%2C274\" alt=\"\" class=\"wp-image-9317\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?w=366&amp;ssl=1 366w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?resize=300%2C225&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/1f9bc026ad771d823fff2dd04ba6a690.jpg?resize=320%2C240&amp;ssl=1 320w\" sizes=\"auto, (max-width: 366px) 100vw, 366px\" 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class=\"wp-block-image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"372\" height=\"281\" data-attachment-id=\"9318\" data-permalink=\"https:\/\/promea2014.com\/blog\/?attachment_id=9318\" data-orig-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?fit=372%2C281&amp;ssl=1\" data-orig-size=\"372,281\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;Yasuyuki&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1565219413&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"\u904b\u52d5AMPK\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?fit=300%2C227&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?fit=372%2C281&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?resize=372%2C281\" alt=\"\" class=\"wp-image-9318\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?w=372&amp;ssl=1 372w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?resize=300%2C227&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/70d2a6fdf07f63480043848009f85d72.jpg?resize=320%2C242&amp;ssl=1 320w\" sizes=\"auto, (max-width: 372px) 100vw, 372px\" 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src=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/92e5ebde4b05682b2d49ed246225dbd8.jpg?resize=640%2C171\" alt=\"\" class=\"wp-image-9319\" srcset=\"https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/92e5ebde4b05682b2d49ed246225dbd8.jpg?w=897&amp;ssl=1 897w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/92e5ebde4b05682b2d49ed246225dbd8.jpg?resize=300%2C80&amp;ssl=1 300w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/92e5ebde4b05682b2d49ed246225dbd8.jpg?resize=768%2C205&amp;ssl=1 768w, https:\/\/i0.wp.com\/promea2014.com\/blog\/wp-content\/uploads\/2019\/08\/92e5ebde4b05682b2d49ed246225dbd8.jpg?resize=320%2C86&amp;ssl=1 320w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure>\n<p><\/p>\n<p><\/p>\n<p>\u4e0a\u306e\u56f3\u306f\u8840\u6db2\u691c\u67fb\u306e\u7d50\u679c\u3067\u3059\u3002\u6301\u4e45\u7cfb\u3001\u30d1\u30ef\u30fc\u7cfb\u3001\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u9806\u306b\u4e26\u3093\u3067\u3044\u307e\u3059\u3002\u9805\u76ee\u306f\u4e0a\u304b\u3089\u904a\u96e2\u8102\u80aa\u9178\u3001\u8840\u7cd6\u5024\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3001\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3001IGF-1\u3067\u3059\u3002\u6301\u4e45\u7cfb\u3067\u306f\u904b\u52d5\u76f4\u5f8c\uff08\uff10h\uff09\u306b\u6210\u9577\u30db\u30eb\u30e2\u30f3\u304c\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u304c\u3001IGF-1\u306f\u5909\u5316\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u5897\u52a0\u50be\u5411\u3067\u306f\u3042\u308a\u307e\u3059\u3002\u30d1\u30ef\u30fc\u7cfb\u306e\u904b\u52d5\u3067\u306f\u904b\u52d5\u5f8c\u306b\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3082\u5927\u304d\u304f\u5897\u52a0\u3057\u3001IGF-1\u3082\u5897\u52a0\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3082\u5897\u52a0\u3057\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u30d1\u30ef\u30fc\u7cfb\u306e\u904b\u52d5\u306f\u6210\u9577\u3001\u5897\u6b96\u3092\u3082\u305f\u3089\u3059\u69d8\u3005\u306a\u3082\u306e\u304c\u5927\u304d\u304f\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u3002\u304c\u3093\u304c\u5897\u52a0\u3057\u3066\u3082\u4e0d\u601d\u8b70\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u3064\u307e\u308a\u3001\u30a2\u30b9\u30ea\u30fc\u30c8\u304c\u62b1\u3048\u308b\u554f\u984c\u306f\u3001\u6b21\u306e\u3088\u3046\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u30fb\u666e\u6bb5\u304b\u3089\u306e\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306b\u30d7\u30e9\u30b9\u3057\u3066\u30b9\u30dd\u30fc\u30c4\u30c9\u30ea\u30f3\u30af\u306a\u3069\u306e\u6db2\u4f53\u306e\u7cd6\u8cea\u3092\u983b\u7e41\u306b\u904e\u5270\u306b\u6442\u53d6\u3059\u308b\u3053\u3068<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u30fb\u7b4b\u8089\u3092\u3064\u3051\u308b\u305f\u3081\u306b\u7b4b\u30c8\u30ec\u3092\u983b\u7e41\u306b\u884c\u3046\u3053\u3068<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u30fb\u540c\u69d8\u306b\u3001\u7b4b\u8089\u3092\u3064\u3051\u308b\u305f\u3081\u306b\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u3092\u983b\u7e41\u306b\u98f2\u3080\u3053\u3068<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u3053\u308c\u3089\u306e3\u3064\u306e\u3053\u3068\u306f\u3059\u3079\u3066mTOR\u3092\u5f37\u304f\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002IGF-1\u3084\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3082\u5897\u52a0\u3057\u307e\u3059\u3002\u7b4b\u8089\u304c\u5897\u5f37\u3057\u3001\u30d1\u30ef\u30fc\u304c\u4ed8\u304d\u3001\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u4e0a\u304c\u308b\u3060\u3051\u306a\u3089\u826f\u3044\u306e\u3067\u3059\u304c\u3001mTOR\u3084\u6210\u9577\u56e0\u5b50\u306e\u904e\u5270\u306a\u6d3b\u6027\u5316\u306f\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u4e0a\u3052\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u3042\u308b\u306e\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u300c\u30b5\u30f3\u30c7\u30fc\u30e2\u30fc\u30cb\u30f3\u30b0\u300d\u306e\u5f35\u672c\u6c0f\u306e\u30b3\u30e1\u30f3\u30c8\u306b\u306f\u3044\u3064\u3082\u4e0d\u5feb\u306a\u6c17\u6301\u3061\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u5f7c\u304c\u3044\u3064\u3082\u8a00\u3063\u3066\u3044\u308b\u300c\u8d70\u308a\u8fbc\u307f\u300d\u304c\u8db3\u308a\u306a\u3044\u3068\u3044\u3046\u306e\u306f\u4e00\u7406\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u8d70\u308a\u8fbc\u307f\u306f\u6301\u4e45\u7cfb\u306e\u904b\u52d5\u3092\u610f\u5473\u3059\u308b\u3068\u8003\u3048\u308b\u3068\u3001\u904e\u5270\u306amTOR\u6d3b\u6027\u5316\u3092\u6291\u5236\u3057\u3066\u304f\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u73fe\u5728\u306e\u8003\u3048\u3067\u306f\u8d70\u308a\u8fbc\u307f\u306f\u3042\u307e\u308a\u610f\u5473\u304c\u306a\u304f\u3001\u7b4b\u30c8\u30ec\u3067\u5fc5\u8981\u306a\u7b4b\u8089\u3092\u5897\u5f37\u3059\u308b\u3053\u3068\u306e\u65b9\u304c\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u30a2\u30c3\u30d7\u306b\u306f\u6709\u76ca\u3067\u3042\u308b\u3068\u3044\u3046\u306e\u304c\u4e3b\u6d41\u3067\u3057\u3087\u3046\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u300cBORN TO RUN\u300d\u3068\u3044\u3046\u672c\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001\u72e9\u731f\u63a1\u96c6\u6642\u4ee3\u306f\u4eba\u9593\u306f\u6301\u4e45\u529b\u3092\u6b66\u5668\u306b\u7372\u7269\u3092\u6355\u3063\u3066\u3044\u305f\u306e\u3067\u306f\u3001\u3068\u3044\u3046\u4eee\u8aac\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><br \/>\n<iframe style=\"width:120px;height:240px;\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" frameborder=\"0\" src=\"https:\/\/rcm-fe.amazon-adsystem.com\/e\/cm?ref=tf_til&amp;t=medmiss-22&amp;m=amazon&amp;o=9&amp;p=8&amp;l=as1&amp;IS1=1&amp;detail=1&amp;asins=4140814144&amp;linkId=8b8ee98b1d994a132b8713c8bae102e1&amp;bc1=ffffff&amp;lt1=_blank&amp;fc1=333333&amp;lc1=0066c0&amp;bg1=ffffff&amp;f=ifr\"><br \/>\n    <\/iframe><br \/>\n<\/p>\n<p><\/p>\n<p>\u30b9\u30d4\u30fc\u30c9\u3067\u306f\u52d5\u7269\u306b\u6575\u3046\u306f\u305a\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3053\u3067\u3001\u6301\u4e45\u6226\u306b\u6301\u3061\u8fbc\u307f\u7372\u7269\u3092\u6355\u307e\u3048\u3066\u3044\u305f\u3068\u3044\u3046\u8003\u3048\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u6642\u4ee3\u306b\u306f\u3082\u3061\u308d\u3093\u7b4b\u30c8\u30ec\u306f\u5b58\u5728\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u81ea\u7136\u3068\u6301\u4e45\u7cfb\u306e\u904b\u52d5\u304c\u306a\u3055\u308c\u3066\u304d\u3066\u304a\u308a\u3001\u305d\u308c\u306b\u4eba\u4f53\u306f\u9069\u5fdc\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u307e\u3057\u3066\u3084\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u98f2\u6599\u306a\u3069\u5b58\u5728\u3059\u308b\u306f\u305a\u3082\u306a\u3044\u306e\u3067\u3001\u4e00\u6c17\u306b\u5358\u4f53\u306e\u5927\u91cf\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u30a2\u30df\u30ce\u9178\u304c\u4f53\u5185\u306b\u5165\u3063\u3066\u304f\u308b\u3053\u3068\u306b\u306f\u9069\u5fdc\u3057\u3066\u3044\u306a\u3044\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002\u52d5\u7269\u306e\u8089\u3092\u98df\u3079\u308b\u3053\u3068\u306f\u3001\u305d\u3053\u306b\u542b\u307e\u308c\u308b\u8102\u80aa\u5206\u3082\u540c\u6642\u306b\u6442\u53d6\u3057\u307e\u3059\u3057\u3001\u540c\u6642\u306b\u91ce\u8349\u306a\u3069\u306e\u98df\u7269\u7e4a\u7dad\u3082\u6442\u53d6\u3057\u3066\u3044\u305f\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u6d88\u5316\u5438\u53ce\u306f\u7de9\u3084\u304b\u306b\u884c\u308f\u308c\u308b\u306f\u305a\u3067\u3059\u3002\u3053\u308c\u306f\u7cd6\u8cea\u6442\u53d6\u6642\u306b\u4ed6\u306e\u6804\u990a\u7d20\u306a\u3069\u3068\u540c\u6642\u306b\u6442\u53d6\u3057\u305f\u65b9\u304c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u304c\u7de9\u3084\u304b\u306b\u306a\u308b\u3053\u3068\u3068\u540c\u3058\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u30d7\u30ed\u30c6\u30a4\u30f3\u306b\u3088\u3063\u3066\u8d77\u304d\u308b\u8840\u7cd6\u5024\u30b9\u30d1\u30a4\u30af\u306a\u3089\u306c\u3001\u30a2\u30df\u30ce\u9178\u30b9\u30d1\u30a4\u30af\u306b\u3088\u308a\u3001\u904e\u5270\u306bmTOR\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u308f\u308c\u307e\u3059\u3002\u3082\u3061\u308d\u3093\u3053\u308c\u306f\u63a8\u6e2c\u3067\u3059\u306e\u3067\u78ba\u8a8d\u3067\u304d\u3066\u3044\u307e\u305b\u3093\u3002\u7b4b\u8089\u3084\u30d1\u30ef\u30fc\u304c\u3082\u3063\u3068\u3082\u91cd\u8981\u8996\u3055\u308c\u308b\u306e\u306f\u3001\u30b9\u30dd\u30fc\u30c4\u3068\u3044\u3046\u3082\u306e\u3092\u8003\u3048\u308c\u3070\u5f53\u7136\u3067\u3059\u304c\u3001\u5fc5\u8981\u4ee5\u4e0a\u306e\u7b4b\u8089\u3084\u30d1\u30ef\u30fc\u306f\u4eba\u9593\u306b\u3068\u3063\u3066\u6709\u76ca\u304b\u3069\u3046\u304b\u306f\u73fe\u5728\u306e\u3068\u3053\u308d\u4e0d\u660e\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u3064\u307e\u308a\u3001\u591a\u304f\u306e\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u7cd6\u8cea\u904e\u5270\u72b6\u614b\uff0bmTOR\u904e\u5270\u6d3b\u6027\u5316\u3001\u6210\u9577\u56e0\u5b50\u904e\u5270\u72b6\u614b\u3067\u3042\u308a\u3001\u305d\u306e\u4ed6\u306e\u4f55\u3089\u304b\u306e\u56e0\u5b50\u304c\u52a0\u308f\u308a\u3001\u304c\u3093\u3092\u767a\u75c7\u3057\u3066\u3057\u307e\u3046\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3046\u306e\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>mTOR\u304c\u305f\u3060\u3067\u3055\u3048\u6d3b\u6027\u5316\u3057\u3066\u3044\u308b\u6210\u9577\u671f\u306e\u5b50\u4f9b\u306b\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u4e0e\u3048\u3066\u3001\u7b4b\u30c8\u30ec\u3092\u3055\u305b\u3066\u3044\u308b\u3053\u3068\u306f\u3001\u3082\u3057\u304b\u3057\u305f\u3089\u6050\u308d\u3057\u3044\u3053\u3068\u3092\u3057\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u7802\u7cd6\u696d\u754c\u304c\u7802\u7cd6\u306e\u6709\u5bb3\u6027\u3092\u305a\u3063\u3068\u96a0\u3057\u3066\u3044\u305f\u3088\u3046\u306b\u3001\u30d7\u30ed\u30c6\u30a4\u30f3\u696d\u754c\u304c\u88cf\u3067\u6697\u8e8d\u3057\u3066\u3044\u305f\u308a\u3057\u3066\u2026\u3002\u5b9f\u969b\u306b\u5473\u306e\u7d20\u306f\u30a2\u30df\u30ce\u9178\u306e\u7814\u7a76\u306e\u305f\u3081\u306b\u6771\u4eac\u5927\u5b66\u3084\u4eac\u90fd\u5927\u5b66\u306b\u591a\u984d\u306e\u8cc7\u91d1\u3092\u51fa\u3057\u3066\u5bc4\u4ed8\u8b1b\u5ea7\u3092\u4f5c\u3063\u3066\u3044\u307e\u3059\u3002\u88fd\u85ac\u4f1a\u793e\u304c\u81ea\u793e\u306e\u88fd\u54c1\u3092\u58f2\u308a\u8fbc\u3080\u305f\u3081\u306b\u5927\u5b66\u306e\u6559\u6388\u306b\u591a\u984d\u306e\u304a\u91d1\u3092\u51fa\u3057\u3066\u3044\u308b\u3053\u3068\u3068\u540c\u3058\u69cb\u56f3\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><\/p>\n<p>\u79c1\u306e\u63a8\u6e2c\u304c\u9593\u9055\u3063\u3066\u3044\u308b\u3068\u826f\u3044\u306e\u3067\u3059\u304c\u2026\u305b\u3081\u3066\u3001\u7cd6\u8cea\u904e\u5270\u6442\u53d6\u306f\u3084\u3081\u305f\u65b9\u304c\u2026<\/p>\n<p><\/p>\n<p><\/p>\n<p><\/p>\n<p><\/p>\n<p class=\"has-text-color has-vivid-cyan-blue-color\">\u300cAll-Cause and Cause-Specific Mortality Among Major League Baseball Players\u300d<\/p>\n<p><\/p>\n<p><\/p>\n<p class=\"has-text-color has-vivid-cyan-blue-color\">\u300c\u30e1\u30b8\u30e3\u30fc\u30ea\u30fc\u30b0\u306e\u91ce\u7403\u9078\u624b\u306b\u304a\u3051\u308b\u5168\u539f\u56e0\u304a\u3088\u3073\u539f\u56e0\u5225\u6b7b\u4ea1\u7387\u300d\uff08\u539f\u6587\u306f<a aria-label=\"\u3053\u3053 (opens in a new tab)\" rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31329214\" 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